Month: September 2020

It is a common heterocyclic compound, the copper-catalyst compound, Copper(I) bromide, cas is 7787-70-4 its synthesis route is as follows.

Example 1 2-(Carboxy-5-nitro-phenyl)malonic acid dimethyl ester A solution of 2-chloro-4-nitrobenzoic acid (75 g, 372 mmol) in dimethyl malonate (900 mL, 20 equivalents) was degassed with nitrogen for 15 min. Copper (I) bromide (5.4 g, 37 mmol) was added in one portion. Sodium methoxide (48.3 g, 894 mmol) was added in one portion to the solution while stirring and the contents exothermed to 48 C. Fifteen minutes later, the contents were heated to 70 C. for 24 hrs. The reaction was complete by nmr. Water (900 mL) was added to the cooled reaction followed by hexanes (900 mL). The aqueous layer was separated, toluene (900 mL) added, the solution filtered through Celite, and the aqueous layer separated. Fresh toluene (1800 mL) was added to the aqueous layer and the biphasic mixture acidified with 6 N aqueous HCl (90 mL). A white precipitate formed and the contents were stirred for 18 hrs. The product was filtered off and dried to give a white solid, 78.1 g (70%, mp 153 C.). IR 2923, 2853, 1750, 1728, 1705, 1458, 1376, 1352, 1305, 1261 cm-1.1 H NMR (CD3)2 SO delta8.37(d,J=2 Hz, 1H), 8.30 (d,J=1 Hz,2H), 5.82(s, 1H),3.83 (s,6H).13 C NMR (CD3)2 SOdelta168.0, 167.3, 149.4, 137.1, 135.8, 132.5, 125.4, 123.7, 54.5, 53.4.Anal. Calcd for C11 H10 NO8:C,48.49; H,3.73; N, 4.71. Found:C, 48.27; H,3.72; N, 4.76.

7787-70-4, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,7787-70-4 ,Copper(I) bromide, other downstream synthetic routes, hurry up and to see

Reference£º
Patent; Pfizer Inc; US5968950; (1999); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

7787-70-4, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Copper(I) bromide, cas is 7787-70-4,the copper-catalyst compound, it is a common compound, a new synthetic route is introduced below.

General procedure: A suspension of copper(I) iodide (0.190 g, 1.0 mmol) and dppc (0.534 g, 1.0 mmol) in20 mL of CH2Cl2 was stirred for 6 h at room temperature to form a light-yellow precipitate.The precipitate was filtered off and purified by recrystallization from CH2Cl2/ethanolto give yellow crystals (Yield: 0.618 g, 85.3%).

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of Copper(I) bromide, 7787-70-4

Reference£º
Article; Li, Qian; Wei, Qiong; Xie, Pei; Liu, Li; Zhong, Xin-Xin; Li, Fa-Bao; Zhu, Nian-Yong; Wong, Wai-Yeung; Chan, Wesley Ting-Kwok; Qin, Hai-Mei; Alharbi, Njud S.; Journal of Coordination Chemistry; vol. 71; 24; (2018); p. 4072 – 4085;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

7787-70-4, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Copper(I) bromide, cas is 7787-70-4,the copper-catalyst compound, it is a common compound, a new synthetic route is introduced below.

General procedure: To a solution of (S,S)-iPr-pheboxH (0.051g, 0.173mmol) in dichloromethane (15mL), the corresponding copper(I) salt CuX (X=Cl, Br, I) (0.347mmol) was added and the mixture stirred at room temperature during 24h. Then, the reaction mixture was filtered via cannula, concentrated under reduced pressure to ca. 2mL and diethyl ether/n-hexane (1:2) (30mL) was added. The resulting solid was washed with n-hexane (3¡Á5mL) and vacuum-dried.

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of Copper(I) bromide, 7787-70-4

Reference£º
Article; Vega, Esmeralda; De Julian, Eire; Borrajo, Gustavo; Diez, Josefina; Lastra, Elena; Gamasa, M. Pilar; Polyhedron; vol. 94; (2015); p. 59 – 66;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

It is a common heterocyclic compound, the copper-catalyst compound, Copper(I) bromide, cas is 7787-70-4 its synthesis route is as follows.

Triethyl phosphite (183g, 1.1 mol) was added to a suspension of copper(I) bromide (164.5 g, 1.15 mol) in toluene (500 ml). The mixture was heated at 80C for 3 h with stirring, then left to cool and settle. The clear solution was decanted from the solid residue and the solvent evaporated on a rotary evaporator at 60C, to provide copper(I) bromide triethyl phosphite complex as a clear colourless oil, 336g (94% crude yield).

7787-70-4, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,7787-70-4 ,Copper(I) bromide, other downstream synthetic routes, hurry up and to see

Reference£º
Patent; ASTRAZENECA AB; ASTRAZENECA UK LIMITED; WO2006/67412; (2006); A1;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Name is Copper(II) trifluoromethanesulfonate, as a common heterocyclic compound, it belongs to copper-catalyst compound, and cas is 34946-82-2, its synthesis route is as follows.

A saturated solution of Cu(OTf)2 in n-butanol was addeddrop by drop to a solution of ligand L5 (40 mg, 0.16 mmol) in n-butanol (3 mL). Diethyl ether was placed on top of theblue butanol layer. After several weeks, deep blue crystalplatelets separated which were isolated by filtration withsuction, washed with a small volume of diethyl ether anddried at air. Yield: 64 mg (91); M.p. 271-275C. – IR (KBr): = 3322 br, 3154 w br, 3063 w, 1641 m, 1613 s, 1453 m, 1284vs, 1256 vs, 1225 vs, 1167 s, 1032 vs, 759 m, 700 s, 639 vs,576 m, 518 m cm-1. – Anal. for C28H30CuF6N10O6S2 (844.27):calcd. C 39.83, H 3.58, N 16.59; found C 40.07, H 3.74, N 16.16.

34946-82-2, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,34946-82-2 ,Copper(II) trifluoromethanesulfonate, other downstream synthetic routes, hurry up and to see

Reference£º
Article; Schroeder, Sven; Frey, Wolfgang; Maas, Gerhard; Zeitschrift fur Naturforschung, B: Chemical Sciences; vol. 71; 6; (2016); p. 683 – 696;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

7787-70-4, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Copper(I) bromide, cas is 7787-70-4,the copper-catalyst compound, it is a common compound, a new synthetic route is introduced below.

A dichloromethane (2mL) solution of macrocycle 1 (12mg, 0.05mmol) was allowed to diffuse slowly through a solution of copper bromide (7.2mg, 0.05mmol) in acetonitrile (2mL) at-60C. Slow evaporation of the orange solution at room temperature afforded compound 5, in a quantitative yield, as colorless crystals suitable for an X-ray diffraction analysis. 1H NMR (CDCl3, 300MHz): delta 5.30-5.20 (m, 2H, =CH2), 4.60-2.20 (m, 16H, CH2). BrC10CuH18O2S2 (377.83): calcd C 31.79, H, 4.80; found: C 31.49, H, 4.52.

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of Copper(I) bromide, 7787-70-4

Reference£º
Article; Carel, Guillaume; Madec, David; Saponar, Alina; Saffon, Nathalie; Nemes, Gabriela; Rima, Ghassoub; Castel, Annie; Journal of Organometallic Chemistry; vol. 755; (2014); p. 72 – 77;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

34946-82-2, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Copper(II) trifluoromethanesulfonate, cas is 34946-82-2,the copper-catalyst compound, it is a common compound, a new synthetic route is introduced below.

A methanolic solution of ligand trans-cyclohexane-1,2-diamine(0.1142 g, 1 mmol) was added dropwise to a clear solution ofCopper(II) trifluoromethanesulfonate (0.1808 g, 0.5 mmol) inmethanol (10 mL). The resultant solution was stirred at roomtemperature for 6 h to produce a dark blue coloured solution. Thediffraction quality crystals of the titled complex were obtaineddirectly by slow evaporation of the deep bluish methanolic solutionat room temperature. Yield: 0.272 g, 75%, m.p: 258 C, Anal. Calc. forC14H32CuF6N4O8S2: C, 26.86; H, 5.15; N, 8.95. Found: C, 26.54; H,5.32, N, 8.78. Selected FT-IR (KBr), cm1: n(NH2) 3332e3279, n(CH2)2967e2861, n(OH) 3463, n(CueN) 628, n(CueO) 514. UVeVis [lmax(nm), epsilon (L mol1 cm1)]: 243 (8940), 548 (89).

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of Copper(II) trifluoromethanesulfonate, 34946-82-2

Reference£º
Article; Agrahari, Bhumika; Layek, Samaresh; Kumari, Shweta; Anuradha; Ganguly, Rakesh; Pathak, Devendra D.; Journal of Molecular Structure; vol. 1134; (2017); p. 85 – 90;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Name is Copper(I) bromide, as a common heterocyclic compound, it belongs to copper-catalyst compound, and cas is 7787-70-4, its synthesis route is as follows.

General procedure: CuI (0.095 g, 0.05 mmol) and PPh3 (0.262 g, 0.10 mmol) in 10 ml of MeCN were stirred for 1 h at 80 C to get a clear solution. To the reaction mixture, a solution of Hnor (0.082 g, 0.05 mmol) in methanol (5 mL) was added dropwise and left on stirring for 4 h. Then the mixture was filtered, and a colorless clear solution was obtained, which was left for slow evaporation leading to crystallization at room temperature. After a few days white crystals were obtained that were suitable for a single-crystal X-ray diffraction analysis.

7787-70-4, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,7787-70-4 ,Copper(I) bromide, other downstream synthetic routes, hurry up and to see

Reference£º
Article; Khan, Rais Ahmad; Dielmann, Fabian; Liu, Xue; Hahn, F. Ekkehardt; Al-Farhan, Khalid; Alsalme, Ali; Reedijk, Jan; Polyhedron; vol. 111; (2016); p. 173 – 178;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

34946-82-2, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Copper(II) trifluoromethanesulfonate, cas is 34946-82-2,the copper-catalyst compound, it is a common compound, a new synthetic route is introduced below.

The complex was prepared according a known procedure [11] , starting from LHMe2 (0.157?g, 1?eq) dissolved in acetone (10?ml) and Et3N (150?mul). A solution of Cu(OTf)2 (0.272?g, 2.1?eq) in acetonitrile (10?ml) was added, and the mixture was stirred for 1?h. The mixture was then concentrated, di-isopropylether (10?ml) was added and the solution was placed at -20?C for 1?week to give the pure complex [Cu2(LMe2)(mu-OH)][OTf] (73?mg, 28%) as a dark solid. ESI-MS (CH3CN), m/z: z?=?1, 589 (M-OTf)+, UV-Vis (CH3CN) (epsilon, M-1?cm-1): 242 (23000), 281 (14000), 326 (16000) 338 (16000), 390 (18000), 760 (185) Anal. Calcd. for C25H27Cu2N6O5S2F3: C, 40.59; H, 3.68; N, 11.36. Found C, 40.62; H, 3.85; N, 11.13.

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of Copper(II) trifluoromethanesulfonate, 34946-82-2

Reference£º
Article; Gennarini, Federica; Kochem, Amelie; Isaac, James; Mansour, Ali-Taher; Lopez, Isidoro; Le Mest, Yves; Thibon-Pourret, Aurore; Faure, Bruno; Jamet, Helene; Le Poul, Nicolas; Belle, Catherine; Simaan, A. Jalila; Reglier, Marius; Inorganica Chimica Acta; vol. 481; (2018); p. 113 – 119;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

7787-70-4, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Copper(I) bromide, cas is 7787-70-4,the copper-catalyst compound, it is a common compound, a new synthetic route is introduced below.

(a) Preparation of 1-(3,4-dimethoxyphenyl)indole-2-carboxylic acid ethyl ester 4-Bromoveratrole (8.8 g, 40 mmol), indole-2-carboxylic acid ethyl ester (1.9 g, 10 mmol), potassium carbonate (1.9 g), copper- (I) bromide (o.2 g), pyridine (2 ml) and nitrobenzene (10 ml) were stirred at 140 C. for 14 hours. After cooling to room temperature, the reaction mixture was applied onto a silica gel flash chromatography column (silica gel: 140 g). The column was subsequently eluted with toluene (500 ml), toluene/acetone (95:5, 500 ml) and toluene/acetone (90:10, 500 ml). 1-(3,4-Dimethoxyphenyl)indole-2-carboxylic acid ethyl ester was eluted with toluene/acetone (90:10) and gave colorless crystals upon evaporation of the solvent. The crystals were triturated with diisopropyl ether, collected by vacuum filtration and dried in the air. Yield: 3.0 g. (92% of theoretical yield) M.pt.: 126-128 C. Rf (toluene/acetone, 9:1)=0.53.

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of Copper(I) bromide, 7787-70-4

Reference£º
Patent; Shell Research Limited; US5399559; (1995); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”