Month: September 2020

It is a common heterocyclic compound, the copper-catalyst compound, Copper(I) bromide, cas is 7787-70-4 its synthesis route is as follows.,7787-70-4

General procedure: Compound 5c was prepared as described for 5a. In this respect, 2 (100 mg, 0.160 mmol) was reacted with [CuBr] (3c) (23 mg, 0.160 mmol). Appropriate work-up, gave 5c (111 mg, 0.144 mmol, 90% based on 2) as a brown solid Mp.: 180 C. IR (KBr, cm-1): nuC?C 1983 (w). 1H NMR (d6-DMSO, delta): 0.24 (s, 9 H, SiMe3), 0.30 (s, 9 H, SiMe3), 7.61 (ddd, 3JH7H6 = 4.7 Hz, 3JH7H8 = 7.3 Hz; 1 H, H7), 7.95 (ddd, 3JH2H1 = 6.3 Hz, 3JH2H3 = 6.6 Hz; 1 H, H2), 8.07 (ddd, 4JH8H6 = 1.5 Hz, 3JH8H7 = 7.3 Hz, 3JH8H9 = 7.8 Hz; 1 H, H8), 8.43 (m, 4JH3H1 = 1.0 Hz, 3JH3H2 = 6.6 Hz; 3JH3H4 = 8.0 Hz, 3JH9H8 = 7.8 Hz; 2 H, H3, H9), 8.67 (dd, 3JH6H7 = 4.7 Hz, 4JH6H8 = 1.5 Hz, 1 H, H6), 8.85 (d, 3JH4H3 = 8.0 Hz, 1 H, H4), 9.05 (dd, 3JH1H2 = 6.3 Hz, 1 H, 4JH1H3 = 1.0 Hz, 1 H, H1), 9.95 (s, 1 H, H5), 10.06 (s, 1 H, H10). ESI-MS (m/z (rel. intens.) in thf: [M++Br] 687 (100), [M+-CuBr + K] 662 (25). Anal. Calc. for C24H28N4CuBrPtSi2 (767.21 g/mol): C, 37.57; H, 3.67; N, 7.30. Found: C, 37.68; H, 3.63; N, 6.92%.

With the complex challenges of chemical substances, we look forward to future research findings about Copper(I) bromide

Reference£º
Article; Al-Anber, Mohammed; Wetzold, Nora; Walfort, Bernhard; Rueffer, Tobias; Lang, Heinrich; Inorganica Chimica Acta; vol. 398; (2013); p. 124 – 131;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.7787-70-4,Copper(I) bromide,as a common compound, the synthetic route is as follows.

7787-70-4, General procedure: To a dry and degassed dichloromethane (10mL) solution of 2,2?-dipyridylamine (1mmol) was added CuX (1mmol). The mixture was kept stirring under nitrogen at ambient temperature. After 1h, a yellow precipitate was formed. To the resulting suspension was added dropwise with stirring a solution of triphenylphosphine (1mmol) in dichloromethane (5mL). The mixture was stirred for another 4h, and then the solvent was evaporated to give a white or yellow residue. The solid residue was extracted with 10mL absolute dichloromethane under the nitrogen atmosphere while the extract was filtered and transferred to a nitrogen-protected flask. 10mL hexane was layered above the resulting solution afforded crystals of the complexes, which were washed with hexane.

7787-70-4 Copper(I) bromide 24593, acopper-catalyst compound, is more and more widely used in various fields.

Reference£º
Article; Wu, Fengshou; Tong, Hongbo; Wang, Kai; Wang, Zheng; Li, Zaoying; Zhu, Xunjin; Wong, Wai-Yeung; Wong, Wai-Kwok; Journal of Photochemistry and Photobiology A: Chemistry; vol. 318; (2016); p. 97 – 103;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

7787-70-4, Copper(I) bromide is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

7787-70-4, a. 2-(carboxy-5-nitro-phenyl)malonic acid dimethyl ester (2) A solution of 2-chloro-4-nitrobenzoic acid (75 g, 372 mmol) in dimethyl malonate (900 mL) was sparged with nitrogen for 15 min. Sodium methoxide (48.3 g, 894 mmol) was added in one portion and the contents exothermed to 480 C. Fifteen minutes later, copper (I) bromide (5.4 g, 37 mmol) was added in one portion and the contents heated to 70 C. for 24 hrs. The reaction was 70% complete by nmr, the contents heated to 85 C. for 6 hrs to completely consume the 2-chloro-4-nitrobenzoic. Water (900 mL) was added to the cooled reaction followed by hexanes (900 mL). The aqueous layer was separated, toluene (900 mL) added, filtered through celite, and aqueous layer separated. Fresh toluene (1800 mL) was added to the aqueous layer and the biphasic mixture acidified with 6N aqueous HCl (90 mL). A white precipitate formed and the contents stirred for 18 hrs. The product was filtered off and dried to give a white soid (78.1 g, 70%) mp=153 C. 1 H NMR (CD3)2 SO delta 78.37 (d, J=2 Hz, 1H), 8.30 (d, J=1 Hz, 2H), 5.82 (s, 1H), (3.83 (s, 6H). 13 C NMR (CD3)2 SO delta 168.0, 167.3, 149.4, 137.1, 135.8, 132.5, 125.4, 123.7, 54.5, 53.4. Anal. Calcd for C11 H10 NO8: C, 48.49; H, 3.73; N, 4.71. Found: C, 48.27; H. 3.72; N, 4.76.

7787-70-4 Copper(I) bromide 24593, acopper-catalyst compound, is more and more widely used in various fields.

Reference£º
Patent; Pfizer INc.; US5919795; (1999); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

As a common heterocyclic compound, it belongs to copper-catalyst compound, name is Copper(I) bromide, and cas is 7787-70-4, its synthesis route is as follows.,7787-70-4

Synthesis of [(SIMes)CuBr]. In an oven-dried vial, copper(I) bromide (0.522 g, 3.63 mmol), SIMes.HCl (0.86 g, 2.52 mmol) and sodium tert-butoxide (0.243 g, 2.52 mmol) were loaded inside a glovebox and stirred in dry THF (18 mL) overnight at room temperature outside of the glovebox. After filtration of the reaction mixture through a plug of Celite, the filtrate was mixed with hexane to form a precipitate. A second filtration afforded 0.808 g (71% yield) of the title complex as an off-white solid.Spectroscopic and analytical data for [(SIMes)CuBr]: 1H NMR (300 MHz, [D6]acetone): delta=7.01 (s, 4H, HAr), 4.16 (s, 4H, NCH2), 2.37 (s, 12H, ArCH3), 2.29 (s, 6H, ArCH3); 13C NMR (75 MHz, CDCl3): delta=202.6 (C, NCN), 138.5 (C, CAr), 135.3 (CH, CAr), 135.0 (C, CAr), 129.7 (CH, CAr), 51.0 (CH2, NCH2), 21.0 (CH3, ArCH3), 18.0 (CH3, ArCH3); Elemental analysis calcd for C21H26BrCuN2 (449.89): C, 56.06; H, 5.83; N, 6.23. Found: C, 55.98; H, 5.64; N, 6.21%.

With the complex challenges of chemical substances, we look forward to future research findings about 7787-70-4,belong copper-catalyst compound

Reference£º
Patent; Institut Catala d’Investigacio Quimica; Institucio Catalana de Recerca i Estudis Avancats; US2009/69569; (2009); A1;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

It is a common heterocyclic compound, the copper-catalyst compound, Copper(II) trifluoromethanesulfonate, cas is 34946-82-2 its synthesis route is as follows.,34946-82-2

Compound 7.5 (4.7 mg, 0.0086 mmol) and copper (II) trifluoromethansulfonate (3.1 mg, 0.0086 mmol) were added to 0.5 mL of MeOH and allowed to stir at room temperature for 2 hours. The MeOH was removedin vacuoto yield a white solid (7.8 mg, quantitative).

With the complex challenges of chemical substances, we look forward to future research findings about Copper(II) trifluoromethanesulfonate

Reference£º
Article; da Silva, Sara R.; Paiva, Stacey-Lynn; Bancerz, Matthew; Geletu, Mulu; Lewis, Andrew M.; Chen, Jijun; Cai, Yafei; Lukkarila, Julie L.; Li, Honglin; Gunning, Patrick T.; Bioorganic and Medicinal Chemistry Letters; vol. 26; 18; (2016); p. 4542 – 4547;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Name is Copper(I) bromide, as a common heterocyclic compound, it belongs to copper-catalyst compound, and cas is 7787-70-4, its synthesis route is as follows.,7787-70-4

0.25 mmol (0.066 g) PPh3 was added to 15 ml CH3CN solution ofcopper(I) bromide (0.036 g, 0.25 mmol) and stirred for 1 h. Acolourless precipitate formed to which the ligand L1 (0.067 g,0.25 mmol) and CHCl3 (10 ml) were added. The mixture was stirredfor 1 h. at room temperature. Orange coloured compoundappeared. It was filtered and dried in air. Single crystals wereobtained by slow diffusion of hexane to the dilute solution of thecompound in chloroform. Yield: 0.105 g (78%). FT-IR (KBr pellet,cm1): 3059(w), 2914(w), 2853(w), 2176 (vw), 2031(w),1603(m),1474(m), 1426(m), 1305(w), 1244(w), 1184(w), 1075(m), 1027(m), 970(w), 797(w), 748(s), 688(vs), 506(s), 483(s), 421(w). Anal.found (calc. for [CuI2(Br)2(L1)(PPh3)2]): C, 57.94 (58.01%); H, 4.49(4.50%); N, 5.19 (5.17%), Cu, 11.79 (11.72%).

With the complex challenges of chemical substances, we look forward to future research findings about Copper(I) bromide

Reference£º
Article; Patra, Goutam K.; Pal, Pankaj K.; Mondal, Jahangir; Ghorai, Anupam; Mukherjee, Anindita; Saha, Rajat; Fun, Hoong-Kun; Inorganica Chimica Acta; vol. 447; (2016); p. 77 – 86;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Name is Copper(II) trifluoromethanesulfonate, as a common heterocyclic compound, it belongs to copper-catalyst compound, and cas is 34946-82-2, its synthesis route is as follows.,34946-82-2

General procedure: To a 50 mL Schlenk flask, 200 mg (0.35 mmol) H4L2, 310 mg(0.86 mmol) of Cu(OTf)2, and 20 mL of dry CH3CN were added and theresulting mixture allowed to stir for 10 min. To the suspension, 1.0 mLof a 2.18M solution of NMe4OH in MeOH was added, resulting in acolor change to a deep green. After stirring for 1 h, solvent was removedunder vacuum to bring the volume to?5 mL. Diethyl ether (20 mL)was added, resulting in the precipitation of green powder that wascollected by filtration, washed with Et2O (2 x 20 mL) and allowed to dry(96 mg, 33%). Crystals were obtained by addition of KOTf to the CH3CNsolution. Repeated attempts to obtain accurate and reproducible CHNanalysis for K(THF)[L2Cu2(CH3CONH)] and the following complexeswere unsuccessful, which we attribute to incomplete combustion.

With the complex challenges of chemical substances, we look forward to future research findings about Copper(II) trifluoromethanesulfonate

Reference£º
Article; Elwell, Courtney E.; Neisen, Benjamin D.; Tolman, William B.; Inorganica Chimica Acta; vol. 485; (2019); p. 131 – 139;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Name is Copper(I) bromide, as a common heterocyclic compound, it belongs to copper-catalyst compound, and cas is 7787-70-4, its synthesis route is as follows.,7787-70-4

A dichloromethane (2mL) solution of macrocycle 1 (12mg, 0.05mmol) was allowed to diffuse slowly through a solution of copper bromide (7.2mg, 0.05mmol) in acetonitrile (2mL) at-60C. Slow evaporation of the orange solution at room temperature afforded compound 5, in a quantitative yield, as colorless crystals suitable for an X-ray diffraction analysis. 1H NMR (CDCl3, 300MHz): delta 5.30-5.20 (m, 2H, =CH2), 4.60-2.20 (m, 16H, CH2). BrC10CuH18O2S2 (377.83): calcd C 31.79, H, 4.80; found: C 31.49, H, 4.52.

With the complex challenges of chemical substances, we look forward to future research findings about Copper(I) bromide

Reference£º
Article; Carel, Guillaume; Madec, David; Saponar, Alina; Saffon, Nathalie; Nemes, Gabriela; Rima, Ghassoub; Castel, Annie; Journal of Organometallic Chemistry; vol. 755; (2014); p. 72 – 77;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Copper(I) bromide, cas is 7787-70-4, it is a common heterocyclic compound, the copper-catalyst compound, its synthesis route is as follows.,7787-70-4

CuBr (0.2 g, 1.39 mmol) wasdissolved in a mixture of dichloromethane (30 ml) and acetonitrile (30 ml) and then 2-benzylpyridine (0.23 g, 1.39 mmol)dissolved in dichloromethane (20 ml) was added. The mixture was stirred for 2 h at room temperature and allowed to standovernight. The next day the colour of the solution was green indicating the oxidation of Cu(I) to Cu(II) and the green solidwas filtered off and recrystallized from methanol. Yield (70%).

As the rapid development of chemical substances, we look forward to future research findings about 7787-70-4

Reference£º
Article; Aguirrechu-Comeron; Pasan; Gonzalez-Platas; Ferrando-Soria; Hernandez-Molina; Journal of Structural Chemistry; vol. 56; 8; (2015); p. 1563 – 1571; Zh. Strukt. Kim.; vol. 56; 8; (2015); p. 1624 – 1632;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

A common heterocyclic compound, the copper-catalyst compound, name is Copper(I) bromide,cas is 7787-70-4, mainly used in chemical industry, its synthesis route is as follows.,7787-70-4

General procedure: The complexes were typically obtained from the reaction of the copper halide (CuX) with the appropriate camphor ligand in THF (3 mL) upon stirring for ca. 18 h at room temperature. Filtration of the precipitate, washing with n-pentane (ca. 6mL) and drying under vacuum affords the Cu(I) complex.

As the rapid development of chemical substances, we look forward to future research findings about 7787-70-4

Reference£º
Article; Fernandes, Tiago A.; Mendes, Filipa; Roseiro, Alexandra P.S.; Santos, Isabel; Carvalho, M. Fernanda N.N.; Polyhedron; vol. 87; (2015); p. 215 – 219;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”