Month: September 2020

As a common heterocyclic compound, it belongs to copper-catalyst compound, name is [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride, and cas is 578743-87-0, its synthesis route is as follows.,578743-87-0

1) 0.2 mmol (NHC) CuCl was dissolved in 3 ml of dry THF in a 20 ml dry glass bottle to form a suspension,The glass was then placed in a glove box refrigerator and frozen at -35 C for 1 h;2) 42.3 mg (0.95 eq) [tBu3PN] Li was dissolved in 3 ml of dry THF in another 20 ml dry glass vial,And then put the glass bottle into the glove box refrigerator,Frozen at -35 C for 1 h;3) Slowly drop the [tBu3PN] Li solution of 2) in a cold (NHC) CuCl suspension in 1) with stirring,After completion of the dropwise addition, the mixture was stirred in a glove box at room temperature for 13 h;4) After completion of the reaction, the solvent (THF) was dried in vacuo to give an oily slag,Followed by the addition of 7 ml of n-pentane or n-hexane to give a suspension,And stirred at room temperature for 15 min,And then through the neutral diatomite short pad filter to remove insoluble matter,The filtrate was placed in a refrigerator and cooled at -35 C for 3-4 h,And then filtered through neutral diatomaceous earth,And then frozen the filtrate,Repeated several times to obtain a clear n-pentane or n-hexane solution,The clear solution was dried to give a white crystalline solid,Ie complex A or B.

With the complex challenges of chemical substances, we look forward to future research findings about 578743-87-0,belong copper-catalyst compound

Reference£º
Patent; Shan, Xida; Bai, Tao; Yang, Yanhui; (31 pag.)CN106243132; (2016); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

As a common heterocyclic compound, it belongs to copper-catalyst compound, name is Copper(II) trifluoromethanesulfonate, and cas is 34946-82-2, its synthesis route is as follows.,34946-82-2

L (0.0424 g, 0.2 mmol), Cu (CF3SO3)2(0.0691g,0.2mmol)H2O (6 mL), CH3CN (4 mL), water and heat 100Oslow C down to room temperature after three days.After opening the autoclave there for X- ray diffraction analysis of the yellow rod-like crystals.Yield: 35%

34946-82-2 is used more and more widely, we look forward to future research findings about Copper(II) trifluoromethanesulfonate

Reference£º
Patent; Tianjin Normal University; Wang, Ying; (10 pag.)CN104557986; (2016); B;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.34946-82-2,Copper(II) trifluoromethanesulfonate,as a common compound, the synthetic route is as follows.

Copper(II) triflate (50.0 mg, 0.14 mmol) was dissolved in methanol (3 ml) and the ligand (42.8 mg, 0.07 mmol) added. The reaction mixture was stirred at r. t. for 16 h. Then the mixture was evaporated to dryness and the resulting green solid recrystallised from dichloromethane and pentane. 5: 23.6 mg, 34.0%. C42H37N5O8S2F6Cu¡¤2CH2Cl2: Anal. Calc. C, 43.16; H, 3.30; N, 5.59. Found: C, 42.72; H, 3.71; N, 5.87%. HR-MS: C40H36N5O263Cu Calc. 681.2239. Found: 681.2202 (100.0), C40H36N5O265Cu Calc. 683.2147. Found 683.2105 (65.1). IR: nunu [cm-1]=3066, 2962, 2870, 1657, 1598, 1535, 1484, 1454, 1265, 1172, 1109, 1032, 953, 756, 639. Magnetic susceptibility in CD2Cl2 (295 K): mueff=1.78muB., 34946-82-2

As the paragraph descriping shows that 34946-82-2 is playing an increasingly important role.

Reference£º
Article; Sauer, Desiree C.; Wadepohl, Hubert; Polyhedron; vol. 81; (2014); p. 180 – 187;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.34946-82-2,Copper(II) trifluoromethanesulfonate,as a common compound, the synthetic route is as follows.

To a solution ofTX-CH2COOH (1 g, 3.7 mmol) in distilled water (50 mL), was addedNaOH (148 mg, 3.7 mmol) to give sodium thioxanthone carboxylate (Na+TX-CH2COO-). Tothis solution Cu(OTf)2 (670 mg, 1.85 mmol) was added upon whichCu(TX)2 formed as a green precipitate. The resultant was separatedby filtration and dried in vacuo to obtain a greensolid. Yield 62%. Elementalanalysis; Calculated: C 66.90%; H 3.37%; O 17.82%; S 11.91%. Found: C 61.13%, H4.75%, O 18.97, S 14.25%. Melting point: 232 C., 34946-82-2

34946-82-2 Copper(II) trifluoromethanesulfonate 2734996, acopper-catalyst compound, is more and more widely used in various fields.

Reference£º
Article; Dadashi-Silab, Sajjad; Yagci, Yusuf; Tetrahedron Letters; vol. 56; 46; (2015); p. 6440 – 6443;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Copper(II) trifluoromethanesulfonate, cas is 34946-82-2, it is a common heterocyclic compound, the copper-catalyst compound, its synthesis route is as follows.,34946-82-2

A solution of Cu(OTf)2 (90.0 mg, 0.249 mM, OTf = trifluormethansulfonate) in methanol was added to a solution of HLpz (53.5 mg,0.250 mM) and triethylamine (25.0 mg, 0.250 mM) in methanol, affording a dark green solution. A solution of excess 4,4-bipyridine (4,4-bipy) was layered on the above solution, from which purple crystals of 1 suitable for X-ray analysis were obtained. Yield: 86 mg, 68%. Anal. Calcd for C34H26Cu2F6N10O8S2: C, 40.52; H, 2.60; N, 13.90. Found: C, 40.27;H, 2.53; N, 13.63. FTIR (KBr): 3447, 1647, 1416, 1380, 1291, 1245, 1224, 1158, 1033,816, 772, 638, 518 cm-1. ESI-MS (MeOH): m/z = 276 [Cu(Lpz)]+, 432 [Cu(Lpz)(4,4-bipy)]+, 490 [Cu(Lpz)2 + H]+.

As the rapid development of chemical substances, we look forward to future research findings about 34946-82-2

Reference£º
Article; Houser, Robert P.; Wang, Zhaodong; Powell, Douglas R.; Hubin, Timothy J.; Journal of Coordination Chemistry; vol. 66; 23; (2013); p. 4080 – 4092;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

7787-70-4,7787-70-4, Copper(I) bromide is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A mixture of CuBr (28.7mg, 0.2mmol) and dppp (82.5mg, 0.2mmol) with an excess of batho (66.5mg, 0.2mmol) were dissolved in CH2Cl2 (5mL) and CH3OH (5mL) solution, stirred at room temperature for 6h. The insoluble residues were removed by filtration, and the filtrate was evaporated slowly at room temperature to yield yellow crystalline products. Yield: 80%. Anal. Calc. for C53H50BrCuN2O2P2: C, 66.84; H, 5.29; N, 2.94. Found: C, 66.97; H, 5.15; N, 2.88%. IR (KBr disc, cm-1): 3378s, 3048w, 2858w, 2580w, 1616w, 1556m, 1515m, 1433s, 1414m, 1229m, 1026s, 998w, 767m, 740s, 698vs, 513s, 482m. 1H NMR (600MHz, CDCl3, 298K): delta 7.87-8.98 (d, 6H, batho CH), 7.56-7.68 (m, 10H, batho CH), 7.41-7.24 (m, 20H, dppp CH), 2.91-2.81 (m, 4H, CH2), 2.78-2.63 (m, 2H, CH2); 31P NMR (400MHz, CDCl3, 298K): -12.25, -14.84.

The synthetic route of 7787-70-4 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Yu, Xiao; Fan, Weiwei; Wang, Guo; Lin, Sen; Li, Zhongfeng; Liu, Min; Yang, Yuping; Xin, Xiulan; Jin, Qionghua; Polyhedron; vol. 157; (2019); p. 301 – 309;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Copper(I) bromide, cas is 7787-70-4, it is a common heterocyclic compound, the copper-catalyst compound, its synthesis route is as follows.,7787-70-4

Cuprous iodide (0.198 g, 1.04 mmol)Adding to a solution of 3,4-bis(diphenylphosphino)-2,5-dimethylthiophene (dpmt) (0.500 g, 1.04 mmol) synthesized in Example 1 in 30 mL of CH2Cl2,The mixture was stirred at room temperature for 5 h. Filter the reaction mixture,The solvent was removed under reduced pressure to give a pale yellow powder.The powder was dissolved in dichloromethane and recrystallized to give 0.615 g of yellow crystals.That is, the complex 1 was found to have a yield of 88.1%.

As the rapid development of chemical substances, we look forward to future research findings about 7787-70-4

Reference£º
Patent; Hubei University; Liu Li; Wei Qiong; (15 pag.)CN108997382; (2018); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.7787-70-4,Copper(I) bromide,as a common compound, the synthetic route is as follows.

7787-70-4, Example 1 2-(Carboxy-5-nitro-phenyl)malonic acid dimethyl ester A solution of 2-chloro-4-nitrobenzoic acid (75g, 372mmol) in dimethyl malonate (900mL, 20 equivalents) was degassed with nitrogen for 15min. Copper (I) bromide (5.4g, 37mmol) was added in one portion. Sodium methoxide (48.3g, 894mmol) was added in one portion to the solution while stirring and the contents exothermed to 48C. Fifteen minutes later, the contents were heated to 70C for 24hrs. The reaction was complete by nmr. Water (900mL) was added to the cooled reaction followed by hexanes (900mL). The aqueous layer was separated, toluene (900mL) added, the solution filtered through Celite, and the aqueous layer separated. Fresh toluene (1800mL) was added to the aqueous layer and the biphasic mixture acidified with 6 N aqueous HCI (90mL). A white precipitate formed and the contents were stirred for 18hrs. The product was filtered off and dried to give a white solid, 78.1g (70%, mp 153C). IR 2923, 2853, 1750, 1728, 1705, 1458, 1376, 1352, 1305, 1261 cm-1. 1H NMR (CD3)2SO delta8.37 (d, J = 2 Hz, 1H), 8.30 (d, J = 1Hz, 2H), 5.82 (s, 1H), 3.83 (s, 6H). 13C NMR (CD3)2SO delta168.0, 167.3, 149.4, 137.1, 135.8, 132.5, 125.4, 123.7, 54.5, 53.4. Anal. Calcd for C11H10NO8: C, 48.49; H, 3.73; N, 4.71. Found: C, 48.27; H, 3.72; N, 4.76.

7787-70-4 Copper(I) bromide 24593, acopper-catalyst compound, is more and more widely used in various fields.

Reference£º
Patent; PFIZER INC.; EP887345; (1998); A1;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

A common heterocyclic compound, the copper-catalyst compound, name is Copper(I) bromide,cas is 7787-70-4, mainly used in chemical industry, its synthesis route is as follows.,7787-70-4

General procedure: To a dry and degassed dichloromethane (10mL) solution of 2,2?-dipyridylamine (1mmol) was added CuX (1mmol). The mixture was kept stirring under nitrogen at ambient temperature. After 1h, a yellow precipitate was formed. To the resulting suspension was added dropwise with stirring a solution of triphenylphosphine (1mmol) in dichloromethane (5mL). The mixture was stirred for another 4h, and then the solvent was evaporated to give a white or yellow residue. The solid residue was extracted with 10mL absolute dichloromethane under the nitrogen atmosphere while the extract was filtered and transferred to a nitrogen-protected flask. 10mL hexane was layered above the resulting solution afforded crystals of the complexes, which were washed with hexane.

As the rapid development of chemical substances, we look forward to future research findings about 7787-70-4

Reference£º
Article; Wu, Fengshou; Tong, Hongbo; Wang, Kai; Wang, Zheng; Li, Zaoying; Zhu, Xunjin; Wong, Wai-Yeung; Wong, Wai-Kwok; Journal of Photochemistry and Photobiology A: Chemistry; vol. 318; (2016); p. 97 – 103;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

34946-82-2, Copper(II) trifluoromethanesulfonate is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Powdered copper metal (0.5g, 7.87 mmol) was added to copper(II)trifluoromethanesulfonate (2.30 g, 6.36 mmol) in acetonitrile (50ml) and the mixture stirred at room temperature for 16 hours. The remaining solids were removed by filtration and the liquid removed in vacuo giving copper(I) tetrakis(acetonitrile) trifluoromethanesulfonate (4.26 g, 11.30 mmol, 88.9%) as a white solid with a melting point of 124C., 34946-82-2

The synthetic route of 34946-82-2 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; KATHOLIEKE UNIVERSITEIT LEUVEN; BINNEMANS, Koen; BROOKS, Niel, Richard; FRANSAER, Jan; SCHALTIN, Stijn; WO2011/109878; (2011); A1;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”