Month: September 2020

34946-82-2, Copper(II) trifluoromethanesulfonate is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

The molar ratio of Cu (CF3SO3) 2 and 4- (3- (4H-1,2,4-triazol-4-yl) phenyl) -4H-1,2,4-triazole (L)(0.0624 g, 0.2 mmol), Cu (CF3SO3) 2 (0.0691 g, 0.2 mmol), H2O (6 mL), 1:CH3CN (4 mL). After three days of hydrothermal treatment at 100 oC, the solution was slowly cooled to room temperature. After opening the kettle for the X-ray single crystal diffraction analysis of the yellow rod-like crystals. Yield: 35% (based on L)., 34946-82-2

The synthetic route of 34946-82-2 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Tianjin Normal University; Wang, Ying; (12 pag.)CN104513260; (2016); B;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

As a common heterocyclic compound, it belongs to copper-catalyst compound, name is Bis(acetylacetone)copper, and cas is 13395-16-9, its synthesis route is as follows.,13395-16-9

A yellow solution of H4L (0.3mmol, 0.068g) in MeOH (5mL) was added to a green solution of Cu(acac)2 (0.30mmol, 0.079g) in dmf (20mL) which was stirred under heating at ~90C. The resulting dark green solution was refluxed for 3h and after cooled at r.t. was layered with Et2O. X-ray quality blue crystals of 1¡¤MeOH were formed after 3weeks. The identity of the crystals was confirmed by unit cell determination (a=b=17.414(1), c=16.751(1) A, alpha=beta=gamma=90, V=5079A3). The crystals were filtered off and dried under vacuum. (Yield: 0.056g, ?65%). The solid was analyzed as solvent free. C44H52Cu4N4O16 requires: C, 46.07; H, 4.57; N, 4.88. Found: C, 45.88; H, 4.54; N, 4.85%. FT-IR (KBr pellets, cm-1): 3413(br,s), 2912(w), 2873(w), 2828(w), 1625(vs), 1603(s), 1543(s), 1473(s), 1448(s), 1399(m), 1385(m), 1338(m), 1300(vs), 1254(m), 1206(m), 1160(m), 1129(m), 1083(m), 1029(s), 980(w), 936(w), 915(m), 875(m), 770(s), 683(s), 633(m), 586(m), 489(m), 454(m).

With the complex challenges of chemical substances, we look forward to future research findings about 13395-16-9,belong copper-catalyst compound

Reference£º
Article; Lazarou, Katerina N.; Savvidou, Aikaterini; Raptopoulou, Catherine P.; Psycharis, Vassilis; Polyhedron; vol. 152; (2018); p. 125 – 137;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

7787-70-4, A common heterocyclic compound, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route., 7787-70-4

Copper bromide (2.223 g, 10.00 mmols) was added to 2-pyridone (1.936 g, 20.38 mmols) dissolved in 10 mL THF, 3 mL of water, and 0.859 g (10.6 mmol) concentrated HBr (?9 M). Dark crystals formed in solution after one week. The product was isolated by vacuum filtration, washed with cold THF, and air-dried to yield 3.41 g (82%) of brown crystals. Single crystals (brown prisms) were obtained by recrystallization in THF/water (10:3). IR (KBr): 3241m, 3150m, 3082m, 2936m (nu N-H), 1638s/1621s (C=O) 1586s, 1536s, 1466m, 1374s, 1277m, 1216m, 1156m, 1091m, 997m, 859m, 775s, 718m, 593m, 539m, 511m cm-1. Anal. Calc. for C20H20N4O4Cu2Br4: C, 29.04; H, 2.44; N, 6.77. Found: C, 28.79; H, 1.76; N, 6.60%.

As the rapid development of chemical substances, we look forward to future research findings about 7787-70-4

Reference£º
Article; Shortsleeves, Kelley C.; Turnbull, Mark M.; Seith, Christopher B.; Tripodakis, Emilia N.; Xiao, Fan; Landee, Christopher P.; Dawe, Louise N.; Garrett, David; De Delgado, Graciela Diaz; Foxman, Bruce M.; Polyhedron; vol. 64; (2013); p. 110 – 121;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

5,10,15,20-Tetraphenyl-21H,23H-porphine copper(II), cas is 14172-91-9, it is a common heterocyclic compound, the copper-catalyst compound, its synthesis route is as follows.,14172-91-9

(a) N-Bromosuccinimide (0.0131 g, 0.0737 mmol) was added with stirring to a solution of 0.02 g (0.0296 mol) of complex 5 in 10 mL of chloroform and the reaction mixture was heated under reflux for 5 min. The mixture was cooled, water was added, the organic layer was separated, washed with water, dried with Na2SO4, concentrated, chromatographed on aluminum oxide (using hexane, chloroform-hexane 1 : 2, and then chloroform as eluent), and reprecipitated from ethanol. Yield 0.016 g (0.0212 mmol), 72%. (b) N-Bromosuccinimide (0.00788 g, 0.0444 mmol) was added with stirring to a solution of 0.02 g (0.0296 mmol) of complex 5 in a mixture of 10 mL of chloroform and 1 mL of DMF, the reaction mixture was kept at ambient temperature for 35 min. The mixture was treated similarly to method a. Yield 0.017 g (0.0225 mmol), 76%. (c) A mixture of 0.02 g (0.0288 mmol) of porphyrin 2 and 0.052 g (0.288 mmol) of Cu(OAc)2 was dissolved in 10 mL of DMF, the reaction mixture was heated to reflux, cooled, poured into water, solid NaCl was added, the precipitate was separated by filtration, washed with water, dried, and chromatographed on aluminum oxide using chloroform as an eluent. Yield 0.02 g (0.0265 mmol), 85%. MS (m/z (Irel, %)): 754 (56) [M]+; for C44H27N4BrCu calcd.: 755. IR (nu, cm-1): 2926 s, 2855 m nu(C-H, Ph), 1790 w, 1680 w, 1488 s nu(C=C, Ph), 1457 m nu(C=N), 1366 m, 1345 s nu(C-N), 1193 s, 1169 w, 1146 m, 1072 m delta(C-H, Ph), 1005 s nu(C-C), 861 s, 796 s gamma(C-H, pyrrole ring), 749 s, 702 s, 689 m gamma(C-H, Ph). For C44H27N4BrCu anal. calcd. (%): C, 69.98; N,7.42; H, 3.60; Br, 10.58. Found (%): C, 69.72; N, 7.30; H, 3.65; Br 9.67.

With the synthetic route has been constantly updated, we look forward to future research findings about 5,10,15,20-Tetraphenyl-21H,23H-porphine copper(II),belong copper-catalyst compound

Reference£º
Article; Chizhova; Shinkarenko; Zav?yalov; Mamardashvili, N. Zh.; Russian Journal of Inorganic Chemistry; vol. 63; 6; (2018); p. 732 – 735; Zh. Neorg. Khim.; vol. 63; 6; (2018); p. 695 – 699,5;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

34946-82-2, Copper(II) trifluoromethanesulfonate is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Compound 7.5 (4.7 mg, 0.0086 mmol) and copper (II) trifluoromethansulfonate (3.1 mg, 0.0086 mmol) were added to 0.5 mL of MeOH and allowed to stir at room temperature for 2 hours. The MeOH was removedin vacuoto yield a white solid (7.8 mg, quantitative)., 34946-82-2

The synthetic route of 34946-82-2 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; da Silva, Sara R.; Paiva, Stacey-Lynn; Bancerz, Matthew; Geletu, Mulu; Lewis, Andrew M.; Chen, Jijun; Cai, Yafei; Lukkarila, Julie L.; Li, Honglin; Gunning, Patrick T.; Bioorganic and Medicinal Chemistry Letters; vol. 26; 18; (2016); p. 4542 – 4547;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact.7787-70-4, Copper(I) bromide it is a common compound, a new synthetic route is introduced below.7787-70-4

General procedure: 0.022g (0.222mmol) of CuCl was added to 0.180g (0.109mmol) of [PPh4]2[1] dissolved in 20mL of MeCN solution at -35C. After stirring the resultant solution for 5min, the yellowish brown solution formed, which was filtered, and the filtrate was concentrated. A solution of Et2O (60mL) was added into the filtrate to precipitate the product at -35C. The precipitate was then washed with Et2O and dried to give [PPh4]2[3a] (0.107g, 0.058mmol, 53% based on [PPh4]2[1]). Similarly, under the same reaction conditions, using CuBr, we have isolated a yellowish brown solid of [PPh4]2[3b] (80% based on [PPh4]2[1]) upon crystallization from Et2O/MeCN.

As the paragraph descriping shows that 7787-70-4 is playing an increasingly important role.

Reference£º
Article; Shieh, Minghuey; Miu, Chia-Yeh; Liu, Yu-Hsin; Chu, Yen-Yi; Hsing, Kai-Jieah; Chiu, Jung-I; Lee, Chung-Feng; Journal of Organometallic Chemistry; vol. 815-816; (2016); p. 74 – 83;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact.7787-70-4, Copper(I) bromide it is a common compound, a new synthetic route is introduced below.7787-70-4

General procedure: 0.018g (0.182mmol) of CuCl was added to 0.340g (0.205mmol) of [PPh4]2[1] dissolved in 20mL of MeCN solution. After stirring the resultant solution for 1hat RT, the yellowish brown solution formed, which was filtered, and solvent was removed in vacuo. The precipitate was washed with Et2O and extracted with THF, then recrystallized with Et2O/MeOH/THF to give [PPh4]2[2a] (0.250g, 0.143mmol, 79% based on CuCl). Similarly, under the same reaction conditions, using CuBr and CuI, we have isolated a yellowish brown solid of [PPh4]2[2b] (96% based on CuBr) and [PPh4]2[2c] (71% based on CuI), respectively, upon crystallization from Et2O/THF.

With the rapid development of chemical substances, we look forward to future research findings about Copper(I) bromide

Reference£º
Article; Shieh, Minghuey; Miu, Chia-Yeh; Liu, Yu-Hsin; Chu, Yen-Yi; Hsing, Kai-Jieah; Chiu, Jung-I; Lee, Chung-Feng; Journal of Organometallic Chemistry; vol. 815-816; (2016); p. 74 – 83;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

As a common heterocyclic compound, it belongs to quinuclidine compound,Quinuclidine-4-carboxylic acid hydrochloride,40117-63-3,Molecular formula: C8H14ClNO133,mainly used in chemical industry, its synthesis route is as follows.,14172-91-9

General procedure: Under the protection of nitrogen, 0.14 mmol of the corresponding 5,10,15,20-tetrakis(4-R-phenyl)porphyrin copper(II)complex was dissolved in 16 ml of CHCl3, to which 0.75 ml of DMFwas added with magnetic stirring. The solution was cooled to 0 Cin an ice bath, and then 0.56 ml of phosphoryl chloride (POCl3) wasslowly added within 20 min. The ice bath was removed and stirringwas continued at room temperature for 1 h, and the solution wascontinuously stirred and heated at 70 C for 24 h. Then 3.606 g ofNaAc and 14.4 ml of distilled water were added in an ice bath andstirring for another 1 h. After separation of the aqueous layer, theorganic layer was washed with 10 ml of distilled water for 3 times,then dried over anhydrous magnesium sulfate and filtered. Thesolvent was removed by rotary evaporation at low temperature toafford a crude product. The crude product was dissolved indichloromethane and subjected to column chromatography overneutral alumina with dichloromethane/petroleum ether (v/v 3:1)as the eluent. The third coloured bandwas collected and the solventwas removed by rotary evaporation to afford a purple powder.

With the complex challenges of chemical substances, we look forward to future research findings about 5,10,15,20-Tetraphenyl-21H,23H-porphine copper(II),belong copper-catalyst compound

Reference£º
Article; Wu, Zhen-Yi; Yang, Sheng-Yan; Journal of Molecular Structure; vol. 1188; (2019); p. 244 – 254;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

7787-70-4, A common heterocyclic compound, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route., 7787-70-4

7787-70-4, Example 1 2-(Carboxy-5-nitro-phenyl)malonic acid dimethyl ester A solution of 2-chloro-4-nitrobenzoic acid (75g, 372mmol) in dimethyl malonate (900mL, 20 equivalents) was degassed with nitrogen for 15min. Copper (I) bromide (5.4g, 37mmol) was added in one portion. Sodium methoxide (48.3g, 894mmol) was added in one portion to the solution while stirring and the contents exothermed to 48C. Fifteen minutes later, the contents were heated to 70C for 24hrs. The reaction was complete by nmr. Water (900mL) was added to the cooled reaction followed by hexanes (900mL). The aqueous layer was separated, toluene (900mL) added, the solution filtered through Celite, and the aqueous layer separated. Fresh toluene (1800mL) was added to the aqueous layer and the biphasic mixture acidified with 6 N aqueous HCI (90mL). A white precipitate formed and the contents were stirred for 18hrs. The product was filtered off and dried to give a white solid, 78.1g (70%, mp 153C). IR 2923, 2853, 1750, 1728, 1705, 1458, 1376, 1352, 1305, 1261 cm-1. 1H NMR (CD3)2SO delta8.37 (d, J = 2 Hz, 1H), 8.30 (d, J = 1Hz, 2H), 5.82 (s, 1H), 3.83 (s, 6H). 13C NMR (CD3)2SO delta168.0, 167.3, 149.4, 137.1, 135.8, 132.5, 125.4, 123.7, 54.5, 53.4. Anal. Calcd for C11H10NO8: C, 48.49; H, 3.73; N, 4.71. Found: C, 48.27; H, 3.72; N, 4.76.

7787-70-4 Copper(I) bromide 24593, acopper-catalyst compound, is more and more widely used in various fields.

Reference£º
Patent; PFIZER INC.; EP887345; (1998); A1;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

34946-82-2, Copper(II) trifluoromethanesulfonate is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

The copper(II) complexes with terpy ligand, [Cu(terpy)(ClO4)2(H2O)] (1) and [Cu(terpy)2](CF3SO3)2¡¤2H2O (2), were synthesized by modification of a previously described method for the preparation of [Cu(terpy)(H2O)](CF3SO3)2 complex [42]. The solution of 1.0mmol of terpy (233.3mg) in 2.0mL of methanol for 1 and ethanol for 2 was added slowly under stirring to the solution containing 1.0mmol of the corresponding copper(II) salt (370.5mg of Cu(ClO4)2¡¤6H2O (1) and 361.7mg of Cu(CF3SO3)2 (2)) in 5.0mL of water. The reaction mixture was stirred at room temperature for 3h. The blue crystals of 1 and 2 suitable for single-crystal X-ray analysis were grown by slow evaporation of the resulting solutions at room temperature. These crystals were filtered off and dried at ambient temperature. The yield (calculated on the basis of terpy) was 73% (375.0mg) for 1 and 78% (337.1mg) for 2.

34946-82-2, The synthetic route of 34946-82-2 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Gli?i?, Biljana ?.; Nikodinovic-Runic, Jasmina; Ilic-Tomic, Tatjana; Wadepohl, Hubert; Veselinovi?, Aleksandar; Opsenica, Igor M.; Djuran, Milo? I.; Polyhedron; vol. 139; (2018); p. 313 – 322;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”