Category: copper-catalyst

7787-70-4, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Copper(I) bromide, cas is 7787-70-4,the copper-catalyst compound, it is a common compound, a new synthetic route is introduced below.

Direct route A round-bottomed flask equipped with a stirring bar was charged with the ligand, SSBn (0.1503g; 0.383mmol) and acetonitrile (10mL) to give a white milky suspension. Anhydrous CuBr (0.0555g, 0.38mmol) was added in one portion under vigourous stirring to give a white suspension which became briefly transparent after a few minutes. The mixture was stirred overnight to give an off-white precipitate; it was sonicated for a few seconds and further stirred for 30min. Diethyl ether (10mL) was added and stirring was continued for 5min to give the product as a white powder which was filtered, washed with diethyl ether (5mL) and dried in air (0.1802g, 0.334mmol, 88%).Sulfur insertion route [CuBr(CSBn)]2 (103mg, 0.102mmol) was partially dissolved in acetonitrile (20mL) in a Schlenk flask. To this was added an excess of sulfur (66mg, 2mmol per sulfur). The mixture was stirred at 70C for 5h after which time the mixture was diluted with 10mL of acetonitrile and filtered. The residue was extracted with acetonitrile (2¡Á10mL). The solvent of the combined organic phases was removed by oil pump vacuum and the off-white solid dried under reduced pressure. Yield=72.6mg (0.135mmol, 66%). 1H NMR (300MHz, DMSO-d6): delta=5.22 (s, 4H, PhCH2), 6.66 (s, 2H, NCH2N), 7.32 (s, 10H, 2¡Á C6H5), 7.50 (overlapping signal, 2H, CH=CH), 7.70 (overlapping signal, 2H, CH=CH). 13C{1H} NMR (DMSO-d6, 100MHz) delta 50.3 (CH2Ph), 56.2 (NCH2N), 118.9 (CHCH), 119.2 (CHCH), 127.9 (overlapping, m/p-C6H5), 128.6 (o-C6H5), 135.9 (i-C6H5), 159.4 (C=S). IR (cm-1): 3390.3, 3092.1, 1569.7, 1495.9, 1451.8, 1408.1, 1231.2, 1190.4, 959.6, 704.5, 671.6. MS (ESI+), m/z 991 [Cu2(SSBn)2Br]+, 847 [Cu(SSBn)2]+, 455. [Cu(SSBn)]+. Elemental analysis: Calc. for C21H20BrCuN4S2: C: 47.06; H: 3.76; N: 10.45. Found: C: 46.96; H: 3.81; N: 10.40.

The chemical industry reduces the impact on the environment during synthesis,7787-70-4,Copper(I) bromide,I believe this compound will play a more active role in future production and life.

Reference£º
Article; Slivarichova, Miriam; Correa ?da Costa, Rosenildo; Nunn, Joshua; Ahmad, Ruua; Haddow, Mairi F.; Sparkes, Hazel A.; Gray, Thomas; Owen, Gareth R.; Journal of Organometallic Chemistry; vol. 847; (2017); p. 224 – 233;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

As a common heterocyclic compound, it belongs to copper-catalyst compound, name is Copper(II) trifluoromethanesulfonate, and cas is 34946-82-2, its synthesis route is as follows.

To a solution of 6.90 g (18.5 mmol) of 5′-bromo-3′-nitro-3,4,5,6-tetrahydro-2H- [l,2′]bipyridinyl-4-yl)-acetic acid in dimethylsulfoxide (100 mL) is added 4.5 mL (41 mmol) of dimethylethylenediamine followed by 4.0 g (39 mmol) of sodiummethanesulfinate and 5.5 g (19 mmol) of copper (II) triflate. The mixture is heated to 130 C for lhour then cooled to room temperature. The mixture is diluted with water and stirred overnight during which time a solid precipitates from solution. The yellow solid is collected by filtration, washed with water and dried on the filter pad to provide 5.00 g (72.6%) of (5′-methanesulfonyl-3′-nitro-3,4,5,6-tetrahydro-2H-[l,2′]bipyridinyl-4-yl)- acetic acid ethyl ester.

34946-82-2, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,34946-82-2 ,Copper(II) trifluoromethanesulfonate, other downstream synthetic routes, hurry up and to see

Reference£º
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; GINN, John David; SORCEK, Ronald John; TURNER, Michael Robert; WU, Di; WU, Frank; WO2011/84985; (2011); A1;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

As a common heterocyclic compound, it belongs to copper-catalyst compound, name is Copper(II) trifluoromethanesulfonate, and cas is 34946-82-2, its synthesis route is as follows.

For the synthesis of (II), a solution of BDPA (0.160 g,0.265 mmol) in THF (5.0 ml) was added to a solution ofCu(triflate)2 (0.095 g, 0.265 mmol) in THF (3.0 ml) under aninert atmosphere and this mixture was stirred for 12 h. The resulting blue solution was diffused with diethyl ether, yielding blue block-shaped crystals after 3 d (yield: 0.110 g, 44%).Elemental analysis calculated: C 38.74, H 2.94, N 6.45, S9.85%; found: C 38.79, H 2.98, N 6.52, S 9.90%. FT-IR (KBr,cm-1); 2980 (w), 2927 (m), 1620 (m), 1455 (m), 1307 (m),1275 (s), 1215 (s), 1155 (s), 1029 (s), 922 (w), 849 (s), 790 (m),770 (m), 737 (m), 697 (s).

34946-82-2, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,34946-82-2 ,Copper(II) trifluoromethanesulfonate, other downstream synthetic routes, hurry up and to see

Reference£º
Article; Sivanesan, Dharmalingam; Youn, Min Hye; Park, Ki Tae; Kim, Hak Joo; Grace, Andrews Nirmala; Jeong, Soon Kwan; Acta Crystallographica Section C: Structural Chemistry; vol. 73; 11; (2017); p. 1024 – 1029;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Name is Copper(II) trifluoromethanesulfonate, as a common heterocyclic compound, it belongs to copper-catalyst compound, and cas is 34946-82-2, its synthesis route is as follows.

To a yellow-brown solution of L1 (60 mg, 0.09 mmol) in THF (3 mL)was added a blue solution of [Cu(OTf)2] (36 mg, 0.09 mmol) at roomtemperature. Upon addition the solution colored to dark green. Themixture solution was stirred for 8 h and after filtered, 20 mL of diethylether were then added to the filtrate to precipitate a green solid. Thesolvents were removed by filtration and the residue was washed withether (3¡Á5 mL) and dried in vacuum to yield product 3 as a blue-greenpowder. The formulation of 3 was deduced from elemental analysis asbeing [Cu(H2O)2(L1)](OTf)2, H2O. Yield: 50 mg, 56%. Crystals suitablefor a X-ray diffraction study were obtained by slow vapor diffusion ofEt2O into a CH3CN solution of 3 in a sealed tube. IR (solid, cm-1):nu(NH) 3334 (w), nu(CO) 1654 (w), nu(CF) 1027 (s). UV-Vis (MeCN) lambdamax,nm (epsilon, M-1cm-1): 257 (28110), 284 (26400), 666 (51), EPR (9.30 GHz;CH3CN; 150 K): g//=2.27, g?=2.05, A//=166 G. Elemental analysis calcd (%) for C39H29CuF6N7O8S2. 1 H2O: C, 45.93; H, 3.46; N, 9.62.Found: C, 45.72; H, 3.17; N, 9.23.

34946-82-2, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,34946-82-2 ,Copper(II) trifluoromethanesulfonate, other downstream synthetic routes, hurry up and to see

Reference£º
Article; Ayad, Massinissa; Schollhammer, Philippe; Le Mest, Yves; Wojcik, Laurianne; Petillon, Francois Y.; Le Poul, Nicolas; Mandon, Dominique; Inorganica Chimica Acta; vol. 497; (2019);,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

7787-70-4, Copper(I) bromide is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

7787-70-4, Copper bromide (2.223 g, 10.00 mmols) was added to 2-pyridone (1.936 g, 20.38 mmols) dissolved in 10 mL THF, 3 mL of water, and 0.859 g (10.6 mmol) concentrated HBr (?9 M). Dark crystals formed in solution after one week. The product was isolated by vacuum filtration, washed with cold THF, and air-dried to yield 3.41 g (82%) of brown crystals. Single crystals (brown prisms) were obtained by recrystallization in THF/water (10:3). IR (KBr): 3241m, 3150m, 3082m, 2936m (nu N-H), 1638s/1621s (C=O) 1586s, 1536s, 1466m, 1374s, 1277m, 1216m, 1156m, 1091m, 997m, 859m, 775s, 718m, 593m, 539m, 511m cm-1. Anal. Calc. for C20H20N4O4Cu2Br4: C, 29.04; H, 2.44; N, 6.77. Found: C, 28.79; H, 1.76; N, 6.60%.

The synthetic route of 7787-70-4 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Shortsleeves, Kelley C.; Turnbull, Mark M.; Seith, Christopher B.; Tripodakis, Emilia N.; Xiao, Fan; Landee, Christopher P.; Dawe, Louise N.; Garrett, David; De Delgado, Graciela Diaz; Foxman, Bruce M.; Polyhedron; vol. 64; (2013); p. 110 – 121;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

34946-82-2, Copper(II) trifluoromethanesulfonate is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Powdered copper metal (0.5g, 7.87 mmol) was added to copper(II)trifluoromethanesulfonate (2.30 g, 6.36 mmol) in acetonitrile (50ml) and the mixture stirred at room temperature for 16 hours. The remaining solids were removed by filtration and the liquid removed in vacuo giving copper(I) tetrakis(acetonitrile) trifluoromethanesulfonate (4.26 g, 11.30 mmol, 88.9%) as a white solid with a melting point of 124C., 34946-82-2

The synthetic route of 34946-82-2 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; KATHOLIEKE UNIVERSITEIT LEUVEN; BINNEMANS, Koen; BROOKS, Niel, Richard; FRANSAER, Jan; SCHALTIN, Stijn; WO2011/109878; (2011); A1;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

A common heterocyclic compound, the copper-catalyst compound, name is Copper(I) bromide,cas is 7787-70-4, mainly used in chemical industry, its synthesis route is as follows.,7787-70-4

General procedure: To a dry and degassed dichloromethane (10mL) solution of 2,2?-dipyridylamine (1mmol) was added CuX (1mmol). The mixture was kept stirring under nitrogen at ambient temperature. After 1h, a yellow precipitate was formed. To the resulting suspension was added dropwise with stirring a solution of triphenylphosphine (1mmol) in dichloromethane (5mL). The mixture was stirred for another 4h, and then the solvent was evaporated to give a white or yellow residue. The solid residue was extracted with 10mL absolute dichloromethane under the nitrogen atmosphere while the extract was filtered and transferred to a nitrogen-protected flask. 10mL hexane was layered above the resulting solution afforded crystals of the complexes, which were washed with hexane.

As the rapid development of chemical substances, we look forward to future research findings about 7787-70-4

Reference£º
Article; Wu, Fengshou; Tong, Hongbo; Wang, Kai; Wang, Zheng; Li, Zaoying; Zhu, Xunjin; Wong, Wai-Yeung; Wong, Wai-Kwok; Journal of Photochemistry and Photobiology A: Chemistry; vol. 318; (2016); p. 97 – 103;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.7787-70-4,Copper(I) bromide,as a common compound, the synthetic route is as follows.

7787-70-4, Example 1 2-(Carboxy-5-nitro-phenyl)malonic acid dimethyl ester A solution of 2-chloro-4-nitrobenzoic acid (75g, 372mmol) in dimethyl malonate (900mL, 20 equivalents) was degassed with nitrogen for 15min. Copper (I) bromide (5.4g, 37mmol) was added in one portion. Sodium methoxide (48.3g, 894mmol) was added in one portion to the solution while stirring and the contents exothermed to 48C. Fifteen minutes later, the contents were heated to 70C for 24hrs. The reaction was complete by nmr. Water (900mL) was added to the cooled reaction followed by hexanes (900mL). The aqueous layer was separated, toluene (900mL) added, the solution filtered through Celite, and the aqueous layer separated. Fresh toluene (1800mL) was added to the aqueous layer and the biphasic mixture acidified with 6 N aqueous HCI (90mL). A white precipitate formed and the contents were stirred for 18hrs. The product was filtered off and dried to give a white solid, 78.1g (70%, mp 153C). IR 2923, 2853, 1750, 1728, 1705, 1458, 1376, 1352, 1305, 1261 cm-1. 1H NMR (CD3)2SO delta8.37 (d, J = 2 Hz, 1H), 8.30 (d, J = 1Hz, 2H), 5.82 (s, 1H), 3.83 (s, 6H). 13C NMR (CD3)2SO delta168.0, 167.3, 149.4, 137.1, 135.8, 132.5, 125.4, 123.7, 54.5, 53.4. Anal. Calcd for C11H10NO8: C, 48.49; H, 3.73; N, 4.71. Found: C, 48.27; H, 3.72; N, 4.76.

7787-70-4 Copper(I) bromide 24593, acopper-catalyst compound, is more and more widely used in various fields.

Reference£º
Patent; PFIZER INC.; EP887345; (1998); A1;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Copper(I) bromide, cas is 7787-70-4, it is a common heterocyclic compound, the copper-catalyst compound, its synthesis route is as follows.,7787-70-4

Cuprous iodide (0.198 g, 1.04 mmol)Adding to a solution of 3,4-bis(diphenylphosphino)-2,5-dimethylthiophene (dpmt) (0.500 g, 1.04 mmol) synthesized in Example 1 in 30 mL of CH2Cl2,The mixture was stirred at room temperature for 5 h. Filter the reaction mixture,The solvent was removed under reduced pressure to give a pale yellow powder.The powder was dissolved in dichloromethane and recrystallized to give 0.615 g of yellow crystals.That is, the complex 1 was found to have a yield of 88.1%.

As the rapid development of chemical substances, we look forward to future research findings about 7787-70-4

Reference£º
Patent; Hubei University; Liu Li; Wei Qiong; (15 pag.)CN108997382; (2018); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

7787-70-4,7787-70-4, Copper(I) bromide is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A mixture of CuBr (28.7mg, 0.2mmol) and dppp (82.5mg, 0.2mmol) with an excess of batho (66.5mg, 0.2mmol) were dissolved in CH2Cl2 (5mL) and CH3OH (5mL) solution, stirred at room temperature for 6h. The insoluble residues were removed by filtration, and the filtrate was evaporated slowly at room temperature to yield yellow crystalline products. Yield: 80%. Anal. Calc. for C53H50BrCuN2O2P2: C, 66.84; H, 5.29; N, 2.94. Found: C, 66.97; H, 5.15; N, 2.88%. IR (KBr disc, cm-1): 3378s, 3048w, 2858w, 2580w, 1616w, 1556m, 1515m, 1433s, 1414m, 1229m, 1026s, 998w, 767m, 740s, 698vs, 513s, 482m. 1H NMR (600MHz, CDCl3, 298K): delta 7.87-8.98 (d, 6H, batho CH), 7.56-7.68 (m, 10H, batho CH), 7.41-7.24 (m, 20H, dppp CH), 2.91-2.81 (m, 4H, CH2), 2.78-2.63 (m, 2H, CH2); 31P NMR (400MHz, CDCl3, 298K): -12.25, -14.84.

The synthetic route of 7787-70-4 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Yu, Xiao; Fan, Weiwei; Wang, Guo; Lin, Sen; Li, Zhongfeng; Liu, Min; Yang, Yuping; Xin, Xiulan; Jin, Qionghua; Polyhedron; vol. 157; (2019); p. 301 – 309;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”