copper related catalyst

578743-87-0, [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

578743-87-0, In a dry double-mouth bottle to place Pt – 2 (0.0594 g, 0.1 mmol), CuClNHC (0.0488 g, 0.1 mmol), vacuum pumping and nitrogen cycle three times, then the nitrogen flow by adding 10 ml ethanol, stirring reflux reaction for 4 hours, cooling to room temperature, then added potassium hexafluorophosphate (0.184 g, 1 mmol), stirring at the room temperature reaction 2 hours, filtered, concentrated filtrate, ethanol: dichloromethane=1:10 column, get the orange solid 0.047 g, and the yield is 40%.

578743-87-0 [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride 0, acopper-catalyst compound, is more and more widely used in various fields.

Reference£º
Patent; Jiangsu University Of Science And Technology; Shi Chao; Li Qiuxia; Zhang Xinghua; (24 pag.)CN108690096; (2018); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact.7787-70-4, Copper(I) bromide it is a common compound, a new synthetic route is introduced below.7787-70-4

Copper bromide (0.079 g, 0.55 mmol) was added to 30 mL of ppdq (0.200 g, 0.55 mmol) In a solution of CH2Cl2, the mixture was stirred at room temperature to form a red suspension, the reaction mixture was filtered, and the solvent was removed under reduced pressure. A red powder was obtained which was recrystallized from CH2Cl2 to give red crystals: 0.238 g, 85.3%.

With the synthetic route has been constantly updated, we look forward to future research findings about Copper(I) bromide,belong copper-catalyst compound

Reference£º
Patent; Hubei University; Liu Li; Guo Bangke; (13 pag.)CN109970769; (2019); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

7787-70-4, A common heterocyclic compound, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route., 7787-70-4

To a solution of CuBr (0.0135 g, 0.094 mmol) in 10 mL of acetonitrile was added dropwise 1 (0.03 g, 0.094 mmol) in dichloromethane (5 mL) at room temperature. The reaction mixture was stirred for 4 h. The solvent was removed under reduced pressure to get 6 as a pale yellow solid. Analtyically pure product of 6 was obtained by recrystallizing the crude product in a 1:2 mixture of dichloromethane and petroleum ether. Yield: 81% (0.035 g). Mp: 158-160 C. Anal. Calc. for C42H44Cu2Br2N2P2: C, 54.66; H, 4.80; N, 3.03. Found: C, 54.95; H, 4.85; N, 2.88%. 1H NMR (400 MHz, CDCl3): delta 7.52-6.83 (m, Ar, 28H), 3.50 (s, CH2, 4H), 2.42 (s, NMe2, 12H). 31P{1H} NMR (162 MHz, CDCl3): delta -16.2 (br s). MS (EI): m/z 845.22 [M-Br]+.

As the paragraph descriping shows that 7787-70-4 is playing an increasingly important role.

Reference£º
Article; Ananthnag, Guddekoppa S.; Edukondalu, Namepalli; Mague, Joel T.; Balakrishna, Maravanji S.; Polyhedron; vol. 62; (2013); p. 203 – 207;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact.7787-70-4, Copper(I) bromide it is a common compound, a new synthetic route is introduced below.7787-70-4

7787-70-4, General procedure: To a solution of (S,S)-iPr-pheboxH (0.051g, 0.173mmol) in dichloromethane (15mL), the corresponding copper(I) salt CuX (X=Cl, Br, I) (0.347mmol) was added and the mixture stirred at room temperature during 24h. Then, the reaction mixture was filtered via cannula, concentrated under reduced pressure to ca. 2mL and diethyl ether/n-hexane (1:2) (30mL) was added. The resulting solid was washed with n-hexane (3¡Á5mL) and vacuum-dried.

As the paragraph descriping shows that 7787-70-4 is playing an increasingly important role.

Reference£º
Article; Vega, Esmeralda; De Julian, Eire; Borrajo, Gustavo; Diez, Josefina; Lastra, Elena; Gamasa, M. Pilar; Polyhedron; vol. 94; (2015); p. 59 – 66;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 7787-70-4, name is Copper(I) bromide. This compound has unique chemical properties. The synthetic route is as follows. 7787-70-4

General procedure: The complexes were typically obtained from the reaction of the copper halide (CuX) with the appropriate camphor ligand in THF (3 mL) upon stirring for ca. 18 h at room temperature. Filtration of the precipitate, washing with n-pentane (ca. 6mL) and drying under vacuum affords the Cu(I) complex.

As the rapid development of chemical substances, we look forward to future research findings about 7787-70-4

Reference£º
Article; Fernandes, Tiago A.; Mendes, Filipa; Roseiro, Alexandra P.S.; Santos, Isabel; Carvalho, M. Fernanda N.N.; Polyhedron; vol. 87; (2015); p. 215 – 219;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.34946-82-2,Copper(II) trifluoromethanesulfonate,as a common compound, the synthetic route is as follows.

To a solution ofTX-CH2COOH (1 g, 3.7 mmol) in distilled water (50 mL), was addedNaOH (148 mg, 3.7 mmol) to give sodium thioxanthone carboxylate (Na+TX-CH2COO-). Tothis solution Cu(OTf)2 (670 mg, 1.85 mmol) was added upon whichCu(TX)2 formed as a green precipitate. The resultant was separatedby filtration and dried in vacuo to obtain a greensolid. Yield 62%. Elementalanalysis; Calculated: C 66.90%; H 3.37%; O 17.82%; S 11.91%. Found: C 61.13%, H4.75%, O 18.97, S 14.25%. Melting point: 232 C., 34946-82-2

34946-82-2 Copper(II) trifluoromethanesulfonate 2734996, acopper-catalyst compound, is more and more widely used in various fields.

Reference£º
Article; Dadashi-Silab, Sajjad; Yagci, Yusuf; Tetrahedron Letters; vol. 56; 46; (2015); p. 6440 – 6443;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 7758-99-8, name is Copper(II) sulfate pentahydrate. This compound has unique chemical properties. The synthetic route is as follows. 7758-99-8

Example 2828.1 28.2[0329] Methyl 4-bromo-3-(trifluoromethoxy)benzoate (28.2). To a solution of 4-amino-3-(trifluoromethoxy)benzoic acid (2.00 g, 9.10 mmol) in MeOH (25.0 mL), was slowly added HCl (1.0 mL, 1.0 M in ether) at room temperature. The resulting reaction mixture was stirred at room temperature overnight. Benzene (20 mL) was added, and the reaction was heated at reflux with a Dean-Stark trap to remove the half volume of the solvent. The rest of the solvent was then evaporated to give the product. MS (ESI) m/e = 235.9 [M+l]+, Calc’d for CgHeF3NOs, 235.1. The crude product was used in the next step without further purification. To an ice-cooled suspension of methyl 4-amino-3- (trifluoromethoxy)benzoate hydrogen chloride salt (8.60 g, 31.70 mmol) in 17.1 mL of water and concentrated HBr (48 %, 17.1 mL), was slowly added a prepared 2.5 M solution of sodium nitrite (2.20 g in 12.7 mL) at 00C. The reaction mixture was stirred at 0 0C for 10 minutes. Meanwhile, a solution OfCuSO4 (6.68 g) in 35 mL of water was heated and sodium bromide (6.52 g) was added. The solution became a green color, and a solution OfNa2SOs (2.80 g) in water (10 mL) was then added to it. The solution was cooled at 0 0C and washed with water (25 x 3 mL). The water was then decanted off. Concentrated HBr (16.7 mL) was added, and the solution became a purple color. The solution of CuBr was slowly added to the diazonium salt (prepared above) at 00C. After addition, the ice-bath was removed, and an oil-bath was placed under the reaction vessel. The reaction mixture was then heated to 600C for 15 minutes, at 80 0C for 15 minutes, and then at 1000C for 20 minutes. The reaction mixture was next cooled to room temperature and made basic with Na2CO3 to a pH 8. The aqueous solution was extracted with EtOAc (100 x 2 mL). The organic layer was washed with brine (25 mL) and dried with MgSO4. The solvent was removed to give the crude product 28.2. 1H NMR (CDCl3) delta 3.96 (s, 3H), 7.75 (d, J= 8.4 Hz5 1 H), 7.86 (d, J= 8.4 Hz, 1 H), 7.98 (s, IH).

The synthetic route of 7758-99-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; AMGEN INC.; WO2008/30520; (2008); A1;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 7787-70-4, Copper(I) bromide. This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.7787-70-4

Example 1 2-(Carboxy-5-nitro-phenyl)malonic acid dimethyl ester A solution of 2-chloro-4-nitrobenzoic acid (75 g, 372 mmol) in dimethyl malonate (900 mL, 20 equivalents) was degassed with nitrogen for 15 min. Copper (I) bromide (5.4 g, 37 mmol) was added in one portion. Sodium methoxide (48.3 g, 894 mmol) was added in one portion to the solution while stirring and the contents exothermed to 48 C. Fifteen minutes later, the contents were heated to 70 C. for 24 hrs. The reaction was complete by nmr. Water (900 mL) was added to the cooled reaction followed by hexanes (900 mL). The aqueous layer was separated, toluene (900 mL) added, the solution filtered through Celite, and the aqueous layer separated. Fresh toluene (1800 mL) was added to the aqueous layer and the biphasic mixture acidified with 6 N aqueous HCl (90 mL). A white precipitate formed and the contents were stirred for 18 hrs. The product was filtered off and dried to give a white solid, 78.1 g (70%, mp 153 C.). IR 2923, 2853, 1750, 1728, 1705, 1458, 1376, 1352, 1305, 1261 cm-1.1 H NMR (CD3)2 SO delta8.37(d,J=2 Hz, 1H), 8.30 (d,J=1 Hz,2H), 5.82(s, 1H),3.83 (s,6H).13 C NMR (CD3)2 SOdelta168.0, 167.3, 149.4, 137.1, 135.8, 132.5, 125.4, 123.7, 54.5, 53.4.Anal. Calcd for C11 H10 NO8:C,48.49; H,3.73; N, 4.71. Found:C, 48.27; H,3.72; N, 4.76.

As the paragraph descriping shows that 7787-70-4 is playing an increasingly important role.

Reference£º
Patent; Pfizer Inc; US5968950; (1999); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

As a common heterocyclic compound, it belongs to copper-catalyst compound, name is Copper(II) trifluoromethanesulfonate, and cas is 34946-82-2, its synthesis route is as follows.,34946-82-2

General procedure: Copper(II) complexes with 4,7-phenanthroline, [Cu(NO3)2(4,7-Hphen)2](NO3)2 (1) and [Cu(CF3SO3)(4,7-phen)2(H2O)2]CF3SO3 (2)were synthesized according to the modified procedure for thepreparation of copper(II) complexes with aromatic N-heterocycles[22]. The solution of 0.5 mmol of CuX2 salt (120.8 mg of Cu(NO3)2-3H2O for 1 and 180.8 mg of Cu(CF3SO3)2 for 2) in 5.0 mL of ethanolwas added slowly under stirring to the solution containing anequimolar amount of 4,7-phen (90.1 mg) in 5.0 mL of ethanol.The reaction mixture was stirred at room temperature for 3-4 h.Complex 1 crystallized from the mother ethanol solution after itscooling in the refrigerator for three days, while those of complex2 were obtained after recrystallization of the solid product precipitatedfrom the reaction mixture in 10.0 mL of acetonitrile. Theblue crystals of 1 and green crystals of 2 suitable for single-crystalX-ray crystallography were filtered off and dried at ambient temperature.Yield (calculated on the basis of 4,7-phen): 99.4 mg(59%) for 1 and 127.0 mg (67%) for 2.

With the complex challenges of chemical substances, we look forward to future research findings about 34946-82-2,belong copper-catalyst compound

Reference£º
Article; Stevanovi?, Nevena Lj.; Andrejevi?, Tina P.; Crochet, Aurelien; Ilic-Tomic, Tatjana; Dra?kovi?, Nenad S.; Nikodinovic-Runic, Jasmina; Fromm, Katharina M.; Djuran, Milo? I.; Gli?i?, Biljana ?.; Polyhedron; vol. 173; (2019);,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

578743-87-0, [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

578743-87-0, Chloro[l ,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene]copper(I) (487.59 mg, 0.25 mmol) and silver triflate (64.2 mg, 0.25 mmol) were mixed under nitrogen in 25 mL flask and 10 mL of dry THF were added. Reaction mixture was stirred at RT for 30 minutes. Solution of 1 ,2-bis(diphenylphosphino)benzene (1 1 1.6 mg, 0.25 mmol) in dry THF (5 mL) was added. Reaction mixture was stirred at RT overnight. Resulting mixture was filtered through Celite and solvent was evaporated on rotovap. Recrystallization from CH2CI2 by vapor diffusion of Et20 gave 130 mg (49.6%) of white needle crystals. Structure confirmed by 1H-NMR spectrum of [(IPR)Cu(dppbz)]OTf (CDCb, 400MHz).

The synthetic route of 578743-87-0 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; THE UNIVERSITY OF SOUTHERN CALIFORNIA; THOMPSON, Mark; DJUROVICH, Peter; KRYLOVA, Valentina; WO2011/63083; (2011); A1;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”