copper related catalyst

As a common heterocyclic compound, it belongs to copper-catalyst compound, name is [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride, and cas is 578743-87-0, its synthesis route is as follows.,578743-87-0

1) 0.2 mmol (NHC) CuCl was dissolved in 3 ml of dry THF in a 20 ml dry glass bottle to form a suspension,The glass was then placed in a glove box refrigerator and frozen at -35 C for 1 h;2) 42.3 mg (0.95 eq) [tBu3PN] Li was dissolved in 3 ml of dry THF in another 20 ml dry glass vial,And then put the glass bottle into the glove box refrigerator,Frozen at -35 C for 1 h;3) Slowly drop the [tBu3PN] Li solution of 2) in a cold (NHC) CuCl suspension in 1) with stirring,After completion of the dropwise addition, the mixture was stirred in a glove box at room temperature for 13 h;4) After completion of the reaction, the solvent (THF) was dried in vacuo to give an oily slag,Followed by the addition of 7 ml of n-pentane or n-hexane to give a suspension,And stirred at room temperature for 15 min,And then through the neutral diatomite short pad filter to remove insoluble matter,The filtrate was placed in a refrigerator and cooled at -35 C for 3-4 h,And then filtered through neutral diatomaceous earth,And then frozen the filtrate,Repeated several times to obtain a clear n-pentane or n-hexane solution,The clear solution was dried to give a white crystalline solid,Ie complex A or B.

With the complex challenges of chemical substances, we look forward to future research findings about 578743-87-0,belong copper-catalyst compound

Reference£º
Patent; Shan, Xida; Bai, Tao; Yang, Yanhui; (31 pag.)CN106243132; (2016); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

As a common heterocyclic compound, it belongs to copper-catalyst compound, name is [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride, and cas is 578743-87-0, its synthesis route is as follows.,578743-87-0

In a flame-dried Schlenk tube under argon atmosphere, [CuCl(IPr)] (1) (0.3mmol, 150mg, 1 equiv.) and KCN (0.3mmol, 19mg, 1 equiv.) were introduced in degassed MeOH (5mL) and the reaction mixture was stirred under reflux (50C) for 4h. After returning to room temperature, the reaction mixture was concentrated to dryness under vacuum. The complex was then dissolved in dichloromethane and filtered through a pad of Celite and concentrated again under vacuum. A purification by recrystallization by slow diffusion of pentane in a THF solution of the complex led to the pure complex (4) as a white powder (143mg, 97% yield). 1H-NMR (CDCl3, 400MHz): delta 1.22 (d, J=6.9Hz, 12H), 1.27 (d, J=6.9Hz, 12H), 2.50 (sept, J=6.9Hz, 4H), 7.14 (s, 2H), 7.30 (d, J=7.8Hz, 4H), 7.50 (t, J=7.8Hz, 4H) ppm. (spectroscopic data in good agreement with the literature) [54].

With the complex challenges of chemical substances, we look forward to future research findings about [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride

Reference£º
Article; Elie, Margaux; Mahoro, Gilbert Umuhire; Duverger, Eric; Renaud, Jean-Luc; Daniellou, Richard; Gaillard, Sylvain; Journal of Organometallic Chemistry; vol. 893; (2019); p. 21 – 31;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 7787-70-4, Copper(I) bromide. This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.7787-70-4

General procedure: To a solution of (S,S)-iPr-pheboxH (0.051g, 0.173mmol) in dichloromethane (15mL), the corresponding copper(I) salt CuX (X=Cl, Br, I) (0.347mmol) was added and the mixture stirred at room temperature during 24h. Then, the reaction mixture was filtered via cannula, concentrated under reduced pressure to ca. 2mL and diethyl ether/n-hexane (1:2) (30mL) was added. The resulting solid was washed with n-hexane (3¡Á5mL) and vacuum-dried.

7787-70-4 is used more and more widely, we look forward to future research findings about Copper(I) bromide

Reference£º
Article; Vega, Esmeralda; De Julian, Eire; Borrajo, Gustavo; Diez, Josefina; Lastra, Elena; Gamasa, M. Pilar; Polyhedron; vol. 94; (2015); p. 59 – 66;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

7787-70-4, A common heterocyclic compound, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route., 7787-70-4

2-(Carboxy-5-nitrophenyl)malonic acid dimethyl ester (8) A solution of 2-chloro-4-nitrobenzoic acid (75 g, 372 mmol) in dimethyl malonate (900 mL) was perfused with nitrogen for 15 min. Sodium methoxide (48.3 g, 894 mmol) was added in one portion and the contents exothermed to 48 C. Fifteen minutes later, copper (I) bromide (5.4 g, 37 mmol) was added in one portion and the contents were heated to 70 C. for 24 hrs. The reaction, which was 70% complete as determined by NMR, was subsequently heated to 85 C. for 5 hrs to completely consume the remaining 2-chloro4-nitrobenzoic acid. Water (900 mL) was added to the cooled reaction followed by hexanes (900 mL). The aqueous layer was separated, toluene (900 mL) was added, the mixture was filtered and aqueous layer separated. Fresh toluene (1800 mL) was added to the aqueous layer and the biphasic mixture acidified with 6N aqueous HCl (90 mL). A white precipitate formed and the contents were stirred for 18 hrs. The product was filtered off and dried to give a white solid (78.1 g, 70%) mp 153 C. 1 H NMR (DMSO) delta8.37 (d, J=2 Hz, 1H), 8.30 (d, J=1 Hz, 2H), 5.82 (s, 1H), 3.83 (s, 6H). 13 C NMR (DMSO) delta168.0, 167.3, 149.4, 137.1, 135.8, 132.5, 125.4, 123.7, 54.5, 53.4. Anal. Calcd for C11 H10 NO8: C, 48.49; H, 3.73; N, 4.71. Found: C, 48.27; H, 3.72; N, 4.76.

With the complex challenges of chemical substances, we look forward to future research findings about Copper(I) bromide

Reference£º
Patent; Pfizer Inc; US6121283; (2000); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.13395-16-9,Bis(acetylacetone)copper,as a common compound, the synthetic route is as follows.

Cu(C5H7O2)2 (13.1 mg, 0.05 mmol) was solubilized in 5 mL of methanoland added to a 5 mL of methanolic solution of HL (24.0 mg,0.1 mmol). The mixture was stirred under reflux for 1 h. Dark greencrystals suitable for X-ray diffraction analysis were obtained after somedays from the mother liquor at room temperature. Yield: 22.9 mg(84.5%). Melting point: Decomposes after 260 C. Molar conductivity(1 mM, DMF): 0.35 Omega-1¡¤cm2¡¤mol-1 Elemental analysis calculated forC26H22O2N8Cu (%): C. 57.61; H. 4.09; N. 20.67. Found (%): C. 57.65; H.3.83; N. 20.64. IR bands (KBr, cm-1): nu(CeO) 1371; nu(C]N) 1580,1557; nu(NeN) 1160; rho(py) 735. ESI-MS [C26H23O2N8Cu]+ calcd./found(m/z)=542.1240, 542.1251.

13395-16-9, The synthetic route of 13395-16-9 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Santiago, Pedro H.O.; Santiago, Mariana B.; Martins, Carlos H.G.; Gatto, Claudia C.; Inorganica Chimica Acta; vol. 508; (2020);,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

7787-70-4, A common heterocyclic compound, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route., 7787-70-4

7787-70-4, General procedure: An acetonitrile solution (5 mL) of cuprous chloride (0.008 g,0.084 mmol) was introduced dropwise to a solution of 1(0.040 g, 0.084 mmol) in dichloromethane (5 mL). The reactionwas allowed to stir at room temperature for 6 h. Afterthat, solvent was evaporated under vacuum to give microcrystallineproduct of 5 as a white solid.

The synthetic route of 7787-70-4 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Kumar, Saurabh; Balakrishna, Maravanji S; Journal of Chemical Sciences; vol. 129; 8; (2017); p. 1115 – 1120;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Copper(II) trifluoromethanesulfonate, cas is 34946-82-2, it is a common heterocyclic compound, the copper-catalyst compound, its synthesis route is as follows.,34946-82-2

A solution of Cu(OTf)2 (90.0 mg, 0.249 mM) in methanol was added to a solution of HLpz (53.5 mg, 0.250 mM) and triethylamine (25.0 mg, 0.250 mM) in methanol, affording a dark green solution. A solution of NaN3 (16.3 mg, 0.250 mM) was then layered on the above solution from which blue crystals of 3 suitable for X-ray analysis were obtained (55 mg, 69% yield). Anal. Calcd for C11H9CuN7O: C,41.44; H, 2.85; N, 30.76. Found: C, 40.56; H, 2.77; N, 30.18. UV-vis (CH3OH) [lambdamax, nm(epsilon, M-1 cm-1)]: 354 (5000), 646 (290). FTIR (KBr): 3430, 2055, 1640, 1376, 1164, 1050,866, 769, 660 cm-1. EPR (9.450 GHz, Mod. Amp. 5.0 G, CH3OH, 77 K): g|| = 2.248,g? 2:037, and A|| = 165 G. ESI-MS (MeOH): m/z = 341 [Cu(Lpz)N3 + Na]+, 659{[Cu(Lpz)N3]2 + Na}+, 977 {[Cu(Lpz)N3]3 + Na}+.

With the rapid development of chemical substances, we look forward to future research findings about Copper(II) trifluoromethanesulfonate

Reference£º
Article; Houser, Robert P.; Wang, Zhaodong; Powell, Douglas R.; Hubin, Timothy J.; Journal of Coordination Chemistry; vol. 66; 23; (2013); p. 4080 – 4092;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact.7787-70-4, Copper(I) bromide it is a common compound, a new synthetic route is introduced below.7787-70-4

General procedure: CuI (0.095 g, 0.05 mmol) and PPh3 (0.262 g, 0.10 mmol) in 10 ml of MeCN were stirred for 1 h at 80 C to get a clear solution. To the reaction mixture, a solution of Hnor (0.082 g, 0.05 mmol) in methanol (5 mL) was added dropwise and left on stirring for 4 h. Then the mixture was filtered, and a colorless clear solution was obtained, which was left for slow evaporation leading to crystallization at room temperature. After a few days white crystals were obtained that were suitable for a single-crystal X-ray diffraction analysis.

7787-70-4 Copper(I) bromide 24593, acopper-catalyst compound, is more and more widely used in various fields.

Reference£º
Article; Khan, Rais Ahmad; Dielmann, Fabian; Liu, Xue; Hahn, F. Ekkehardt; Al-Farhan, Khalid; Alsalme, Ali; Reedijk, Jan; Polyhedron; vol. 111; (2016); p. 173 – 178;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.578743-87-0,[1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride,as a common compound, the synthetic route is as follows.,578743-87-0

Chloro[l ,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene]copper(I) (121.9 mg, 0.25 mmol) and silver triflate (64.2 mg, 0.25 mmol) were mixed under nitrogen in 25 mL flask and 10 mL of dry THF were added. Reaction mixture was stirred at RT for 30 minutes. Solution of 1 , 10-phenanthroline (45.05 mg, 0.25 mmol) in dry THF (5 mL) was added. Reaction mixture turned yellow and was stirred at RT overnight. Resulting mixture was filtered through Celite and solvent was evaporated on rotovap. Recrystallization from CH2Ch by vapor diffusion of Et20 gave 120 mg (61.4%) of yellow crystals. Anal, calcd. for C40H44CUF3N4O3S: C, 61.48; H, 5.68; N, 7.17; Found: C, 61.06; H, 5.61; N, 7.14. Structure was confirmed by IH-NMR spectrum of [(IPR)Cu(phen)]OTf (CDCb, 400MHz).

The synthetic route of 578743-87-0 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; THE UNIVERSITY OF SOUTHERN CALIFORNIA; THOMPSON, Mark; DJUROVICH, Peter; KRYLOVA, Valentina; WO2011/63083; (2011); A1;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

5,10,15,20-Tetraphenyl-21H,23H-porphine copper(II), cas is 14172-91-9, it is a common heterocyclic compound, the copper-catalyst compound, its synthesis route is as follows.

Copper(II) meso-tetra(4-carboxyphenyl)porphine (8.8 mg, 0.01 mmol) and fumaric acid (9.9 mg, 0.06 mmol) were dissolved in DMF (5 mL) in a small capped vial, sonicated to ensure homogeneity and heated to 80 C for 72 h, followed by 72 h of evaporation in a crystallizing dish, yielding diffraction quality fibrous red crystals. numax/cm-1: 3403 (C(sp2)H), 2770 (OH), 1390-1280 (C=O). 1600-1450 (CC), 1320 (CO), 1380 (CN), 1006 (CuTCPP), 790-600 (CH). Found: C, 59.91; H, 5.17; N, 9.54; O, 18.40. Calc. for C66H68CuN10O14: C, 61.50; H, 5.32; N, 10.87; O, 17.38., 14172-91-9

With the rapid development of chemical substances, we look forward to future research findings about 14172-91-9

Reference£º
Article; Fidalgo-Marijuan, Arkaitz; Amayuelas, Eder; Barandika, Gotzone; Bazan, Begona; Urtiaga, Miren Karmele; Arriortua, Maria Isabel; Molecules; vol. 20; 4; (2015); p. 6683 – 6699;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”