Related Products of 13395-16-9, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.13395-16-9, Name is Bis(acetylacetone)copper, molecular formula is C10H16CuO4. In a article£¬once mentioned of 13395-16-9
A Copper-Catalyzed Tandem C?H ortho-Hydroxylation and N?N Bond-Formation Transformation: Expedited Synthesis of 1-(ortho-Hydroxyaryl)-1H-indazoles
A facile, one-pot synthesis of 1H-indazoles featuring a Cu-catalyzed C?H ortho-hydroxylation and N?N bond-formation sequence with the use of pure oxygen as the terminal oxidant was developed. The reaction of readily available 2-arylaminobenzonitriles with various organometallic reagents led to ortho-arylamino N?H ketimine species. Subsequent Cu-catalyzed hydroxylation at the ortho position of the aromatic ring followed by N?N bond formation in DMSO under a pure-oxygen atmosphere afforded a wide variety of 1-(ortho-hydroxyaryl)-1H-indazoles in good to excellent yields. This efficient method does not require the utilization of noble-metal catalysts, elaborate directing groups, or privileged ligands.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 13395-16-9
Reference£º
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”