Tag: 361.6842

Catalytic asymmetric [4+1] spiroannulation of α-bromo-β-naphthols with azoalkenes by an electrophilic dearomatization/S_RN1-debromination approach was written by Bai, Lu;Luo, Xin;Ge, Yicong;Wang, Hui;Liu, Jingjing;Wang, Yaoyu;Luan, Xinjun. And the article was included in CCS Chemistry in 2022.Recommanded Product: Copper(II) trifluoromethanesulfonate This article mentions the following:

An enantioselective [4+1]-spiroannulation of α-bromo-β-naphthols with azoalkenes has been developed for the one-step construction of a new class of pyrazoline-based spirocyclic mols. Using chiral Cu(II)/Box catalysts, asym. induction was achieved with high levels of enantioselectivity [up to 99:1 enantiomeric ratio (er)]. Notably, α-chloro- and α-iodo-substituted β-naphthols were also tolerated by this reaction. Mechanistic studies disclosed that this process was triggered by electrophile-facilitated dearomatization of α-bromo-β-naphthols and followed by the debromination via S_RN1-substitution with an in situ-formed N-nucleophile. The chiral copper(II)-species, bound with azoalkene moiety, was assumed to control the enantio-discrimination over the naphthoxy C-radical that was generated from the debromination step. Moreover, the potential utility of this protocol was greatly amplified by the derivatization of spirocyclic products through oxidative dearomatization of the other aromatic ring in the naphthyl fragment, providing a rather attractive route for the rapid generation of synthetically more valuable doubly dearomatized architectures. In the experiment, the researchers used many compounds, for example, Copper(II) trifluoromethanesulfonate (cas: 34946-82-2Recommanded Product: Copper(II) trifluoromethanesulfonate).

Copper(II) trifluoromethanesulfonate (cas: 34946-82-2) belongs to copper catalysts. The applications of Copper-based nanoparticles have received great attention due to the earth-abundant, low toxicity and inexpensive. Copper nanoparticles can also catalyze the coupling reaction of nitrogen-containing nucleophiles, phenols, thiols, xanthogenates, selenium ruthenium nucleophiles and the like.Recommanded Product: Copper(II) trifluoromethanesulfonate

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Enantio- and Diastereoselective Cu(II)-Catalyzed Conjugate Borylation/Michael Addition Cascade: Synthesis of Spiroindane Boronates was written by Khalse, Laxman Devidas;Gorad, Sachin S.;Ghorai, Prasanta. And the article was included in Organic Letters in 2022.Electric Literature of C2CuF6O6S2 This article mentions the following:

The authors report a Cu(II)-(S,S)-ⁱPr-FOXAP-catalyzed borylative Michael/Michael addition cascade cyclization of unsym. dienone for the synthesis of highly substituted and functionalized all-C spiroindane boronates under mild conditions. Optically active spiroindanes bearing boronic ester were obtained with excellent yields and good to excellent enantioselectivities (≤97% ee) and diastereoselectivities (up to >20:1 dr). Scale-up synthesis of this method and synthetic transformations of spiroindane boronates are also illustrated. In the experiment, the researchers used many compounds, for example, Copper(II) trifluoromethanesulfonate (cas: 34946-82-2Electric Literature of C2CuF6O6S2).

Copper(II) trifluoromethanesulfonate (cas: 34946-82-2) belongs to copper catalysts. The evolution of transition metal catalysts has attained a stage of civilization that authorizes for an extensive scope of chemical bonds formation partners to be combined efficiently. Copper of different valence states can be used to catalyze the coupling reaction, especially the Ullmann coupling reaction. Electric Literature of C2CuF6O6S2

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

One-pot synthesis of α-sulfoximinophosphonate via Kabachnik-Fields reaction was written by Natarajan, K.;Sharma, Suraj;Irfana Jesin, C. P.;Kataria, Ramesh;Nandi, Ganesh Chandra. And the article was included in Organic & Biomolecular Chemistry in 2022.Electric Literature of C2CuF6O6S2 This article mentions the following:

Herein, we disclose a novel approach for the synthesis of hitherto unknown α-sulfoximinophosphonate via the Kabachnik-Fields reaction of aldehyde, dialkylphosphite and sulfoximine in the presence of InCl₃ in THF at 70°C. α-Sulfoximinophosphonate is synthesized in good yields and its synthetic utilities are proved by functionalizing bromine through the Pd-catalyzed Suzuki-Miyaura cross-coupling reaction and reduction of a nitro group through the Bećhamp reduction In the experiment, the researchers used many compounds, for example, Copper(II) trifluoromethanesulfonate (cas: 34946-82-2Electric Literature of C2CuF6O6S2).

Copper(II) trifluoromethanesulfonate (cas: 34946-82-2) belongs to copper catalysts. The transition metal-catalyzed chemical transformation of organic electrophiles and organometallic reagents has turned up as an exceedingly robust synthetic tool. Copper nanoparticles can catalyze the Ullmann coupling reaction in a wide range of applications.Electric Literature of C2CuF6O6S2

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Catalytic Regio- and Enantioselective Protonation for the Synthesis of Chiral Allenes: Synergistic Effect of the Counterion and Water was written by Lin, Qianchi;Zheng, Sujuan;Chen, Long;Wu, Jin;Li, Jinzhao;Liu, Peizhi;Dong, Shunxi;Liu, Xiaohua;Peng, Qian;Feng, Xiaoming. And the article was included in Angewandte Chemie, International Edition in 2022.Name: Copper(II) trifluoromethanesulfonate This article mentions the following:

A highly enantioselective tandem Pudovik addition/[1,2]-phospha-Brook rearrangement of α-alkynylketoamides with diarylphosphine oxides was achieved with a N,N’-dioxide/Sc^III complex as the catalyst. This protocol features broad substrate scope, high regio- and enantioselectivity, and good functional-group compatibility, providing a straightforward route to various trisubstituted allenes with a diarylphosphinate functionality in good yields with high enantioselectivities (up to 97% yield, 96% ee). Control experiments and theor. calculations revealed that a synergistic effect of the counterion and water was critical for the regio- and enantioselective protonation after [1,2]-phospha-Brook rearrangement. The synthetic utility of this methodol. was demonstrated by the conversion of products into complex bridged polycyclic architectures through intramol. dearomatizing arene/allene cycloaddition In the experiment, the researchers used many compounds, for example, Copper(II) trifluoromethanesulfonate (cas: 34946-82-2Name: Copper(II) trifluoromethanesulfonate).

Copper(II) trifluoromethanesulfonate (cas: 34946-82-2) belongs to copper catalysts. The applications of Copper-based nanoparticles have received great attention due to the earth-abundant, inexpensive and low toxicity. The copper-mediated C-C, C-O, C-N, and C-S bond formation is a part of one oldest reaction, emphasizing the Ullmann cross-coupling reaction.Name: Copper(II) trifluoromethanesulfonate

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Structural and Dynamic Disorder, Not Ionic Trapping, Controls Charge Transport in Highly Doped Conducting Polymers was written by Jacobs, Ian E.;D’avino, Gabriele;Lemaur, Vincent;Lin, Yue;Huang, Yuxuan;Chen, Chen;Harrelson, Thomas F.;Wood, William;Spalek, Leszek J.;Mustafa, Tarig;O’Keefe, Christopher A.;Ren, Xinglong;Simatos, Dimitrios;Tjhe, Dion;Statz, Martin;Strzalka, Joseph W.;Lee, Jin-Kyun;McCulloch, Iain;Fratini, Simone;Beljonne, David;Sirringhaus, Henning. And the article was included in Journal of the American Chemical Society in 2022.COA of Formula: C2CuF6O6S2 This article mentions the following:

Doped organic semiconductors are critical to emerging device applications, including thermoelecs., bioelectronics, and neuromorphic computing devices. It is commonly assumed that low conductivities in these materials result primarily from charge trapping by the Coulomb potentials of the dopant counterions. Here, we present a combined exptl. and theor. study rebutting this belief. Using a newly developed doping technique based on ion exchange, we prepare highly doped films with several counterions of varying size and shape and characterize their carrier d., elec. conductivity, and paracryst. disorder. In this uniquely large data set composed of several classes of high-mobility conjugated polymers, each doped with at least five different ions, we find elec. conductivity to be strongly correlated with paracryst. disorder but poorly correlated with ionic size, suggesting that Coulomb traps do not limit transport. A general model for interacting electrons in highly doped polymers is proposed and carefully parametrized against atomistic calculations, enabling the calculation of elec. conductivity within the framework of transient localization theory. Theor. calculations are in excellent agreement with exptl. data, providing insights into the disorder-limited nature of charge transport and suggesting new strategies to further improve conductivities. In the experiment, the researchers used many compounds, for example, Copper(II) trifluoromethanesulfonate (cas: 34946-82-2COA of Formula: C2CuF6O6S2).

Copper(II) trifluoromethanesulfonate (cas: 34946-82-2) belongs to copper catalysts. The applications of Copper-based nanoparticles have received great attention due to the earth-abundant, low toxicity and inexpensive. It is clear from the impact copper catalysis has had on organic synthesis that copper should be considered a first line catalyst for many organic reactions.COA of Formula: C2CuF6O6S2

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Monophosphoniums as Effective Photoredox Organocatalysts for Visible Light-Regulated Cationic RAFT Polymerization was written by Yang, Zan;Chen, Jianxu;Liao, Saihu. And the article was included in ACS Macro Letters in 2022.Category: copper-catalyst This article mentions the following:

Visible light-regulated metal-free polymerizations have attracted considerable attention for macromol. syntheses in recent years. However, few organic photocatalysts show high efficiency and strict photocontrol in cationic polymerizations Herein, we introduce monophosphonium-doped polycyclic arenes as an organic photocatalyst, which features the high tunability, broad redox window, long excited state lifetime, and excellent temporal control in the cationic reversible addition-fragmentation chain transfer polymerization of vinyl ethers. A correlation of the catalytic performance and the photophys. and electrochem. properties of photocatalysts is also discussed. In the experiment, the researchers used many compounds, for example, Copper(II) trifluoromethanesulfonate (cas: 34946-82-2Category: copper-catalyst).

Copper(II) trifluoromethanesulfonate (cas: 34946-82-2) belongs to copper catalysts. The transition metal-catalyzed chemical transformation of organic electrophiles and organometallic reagents has turned up as an exceedingly robust synthetic tool. These ligands enable the reaction promoted in mild condition. The reaction scope has also been greatly expanded, rendering this copper-based cross-coupling attractive for both academia and industry. Category: copper-catalyst

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Synthesis of β-Polychlorinated Alkynes Enabled by Copper-Catalyzed Multicomponent Reaction was written by Wang, Qiuzhu;Wang, Mengning;Wu, Qianhui;Ma, Mengtao;Zhao, Binlin. And the article was included in Organic Letters in 2022.Application In Synthesis of Copper(II) trifluoromethanesulfonate This article mentions the following:

Functional mols. bearing polychlorinated moieties usually play versatile roles in organic synthesis and biochem. A copper-catalyzed multicomponent polychloro-carboalkynylation of alkenes presents an efficient and operationally simple approach for the synthesis of β-polychlorinated alkynes. Mechanistic experiments were conducted demonstrating that an in situ generated copper acetylide complex was the real catalyst and reactive intermediate during the copper-catalytic cycle. And enantioselective exploration demonstrated potential application for the synthesis of chiral β-polychlorinated alkynes. In the experiment, the researchers used many compounds, for example, Copper(II) trifluoromethanesulfonate (cas: 34946-82-2Application In Synthesis of Copper(II) trifluoromethanesulfonate).

Copper(II) trifluoromethanesulfonate (cas: 34946-82-2) belongs to copper catalysts. The evolution of transition metal catalysts has attained a stage of civilization that authorizes for an extensive scope of chemical bonds formation partners to be combined efficiently. Copper of different valence states can be used to catalyze the coupling reaction, especially the Ullmann coupling reaction. Application In Synthesis of Copper(II) trifluoromethanesulfonate

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”