Tag: M.W:100-200

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact.7787-70-4, Copper(I) bromide it is a common compound, a new synthetic route is introduced below.7787-70-4

Copper bromide (0.079 g, 0.55 mmol) was added to 30 mL of ppdq (0.200 g, 0.55 mmol) In a solution of CH2Cl2, the mixture was stirred at room temperature to form a red suspension, the reaction mixture was filtered, and the solvent was removed under reduced pressure. A red powder was obtained which was recrystallized from CH2Cl2 to give red crystals: 0.238 g, 85.3%.

With the synthetic route has been constantly updated, we look forward to future research findings about Copper(I) bromide,belong copper-catalyst compound

Reference£º
Patent; Hubei University; Liu Li; Guo Bangke; (13 pag.)CN109970769; (2019); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

7787-70-4, Copper(I) bromide is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

7787-70-4, General procedure: The complexes were prepared according to the following method [14]: 1mmol of copper(I) bromide or copper(I) chloride is stirred in methanol until complete dissolution. Then, 2.1 mmol of the corresponding phosphine ligand was added. The mixture was stirred at 60C for 30min. under nitrogen atmosphere. A microcrystalline precipitate was obtained by concentration of the solution at reduced pressure. The solid product was dissolved in a dichloromethane/methanol mixture and the solution was gradually cooled to 4C to give an air stable and colorless crystalline solid suitable for X-ray single-crystal diffraction studies.

7787-70-4 Copper(I) bromide 24593, acopper-catalyst compound, is more and more widely used in various fields.

Reference£º
Article; Espinoza, Sully; Arce, Pablo; San-Martn, Enrique; Lemus, Luis; Costamagna, Juan; Faras, Liliana; Rossi, Miriam; Caruso, Francesco; Guerrero, Juan; Polyhedron; vol. 85; (2015); p. 405 – 411;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 7787-70-4, Copper(I) bromide. This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.7787-70-4

Compound 2 (23mg, 0.05mmol) in dichloromethane (2mL) was slowly added on a solution of copper bromide (7.2mg, 0.05mmol) in acetonitrile (2mL) at-60C. The orange-red solution resulting from complete diffusion was slowly evaporated at r.t. to afford compound 6 (quantitative yield) as colorless crystals suitable for an X-ray diffraction analysis. Mp=93C. 1H NMR (CDCl3, 300MHz): delta 5.21 (s, 4H, =CH2), 4.30-3.95 (m, 8H, CH2-C=), 4.00-2.35 (m, 24H). Br2C20Cu2H36O4S4 (755.56): calcd C 31.79, H, 4.80; found: C 31.09, H, 4.22.

With the rapid development of chemical substances, we look forward to future research findings about 7787-70-4

Reference£º
Article; Carel, Guillaume; Madec, David; Saponar, Alina; Saffon, Nathalie; Nemes, Gabriela; Rima, Ghassoub; Castel, Annie; Journal of Organometallic Chemistry; vol. 755; (2014); p. 72 – 77;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Copper(I) bromide, A common heterocyclic compound, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route. 7787-70-4

Copper bromide (0.079 g, 0.55 mmol) was added to 30 mL of ppdq (0.200 g, 0.55 mmol) In a solution of CH2Cl2, the mixture was stirred at room temperature to form a red suspension, the reaction mixture was filtered, and the solvent was removed under reduced pressure. A red powder was obtained which was recrystallized from CH2Cl2 to give red crystals: 0.238 g, 85.3%.

As the paragraph descriping shows that 7787-70-4 is playing an increasingly important role.

Reference£º
Patent; Hubei University; Liu Li; Guo Bangke; (13 pag.)CN109970769; (2019); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

7787-70-4, A common heterocyclic compound, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route., 7787-70-4

The ligand (50.0 mg, 0.11 mmol) was added to a suspension of copper(II) halogenide (0.11 mmol) in methanol (3 ml). The mixture was stirred at r. t. for 16 h. The precipitate was then filtered off and dried in vacuo. The pure compounds were obtained by recrystallization from dichloromethane and pentane.

With the rapid development of chemical substances, we look forward to future research findings about Copper(I) bromide

Reference£º
Article; Sauer, Desiree C.; Wadepohl, Hubert; Polyhedron; vol. 81; (2014); p. 180 – 187;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact.7787-70-4, Copper(I) bromide it is a common compound, a new synthetic route is introduced below.7787-70-4

a. 2-(carboxy-5-nitro-phenyl)malonic acid dimethyl ester (2) A solution of 2-chloro-4-nitrobenzoic acid (75 g, 372 mmol) in dimethyl malonate (900 mL) was sparged with nitrogen for 15 min. Sodium methoxide (48.3 g, 894 mmol) was added in one portion and the contents exothermed to 480 C. Fifteen minutes later, copper (I) bromide (5.4 g, 37 mmol) was added in one portion and the contents heated to 70 C. for 24 hrs. The reaction was 70% complete by nmr, the contents heated to 85 C. for 6 hrs to completely consume the 2-chloro-4-nitrobenzoic. Water (900 mL) was added to the cooled reaction followed by hexanes (900 mL). The aqueous layer was separated, toluene (900 mL) added, filtered through celite, and aqueous layer separated. Fresh toluene (1800 mL) was added to the aqueous layer and the biphasic mixture acidified with 6N aqueous HCl (90 mL). A white precipitate formed and the contents stirred for 18 hrs. The product was filtered off and dried to give a white soid (78.1 g, 70%) mp=153 C. 1 H NMR (CD3)2 SO delta 78.37 (d, J=2 Hz, 1H), 8.30 (d, J=1 Hz, 2H), 5.82 (s, 1H), (3.83 (s, 6H). 13 C NMR (CD3)2 SO delta 168.0, 167.3, 149.4, 137.1, 135.8, 132.5, 125.4, 123.7, 54.5, 53.4. Anal. Calcd for C11 H10 NO8: C, 48.49; H, 3.73; N, 4.71. Found: C, 48.27; H. 3.72; N, 4.76.

With the synthetic route has been constantly updated, we look forward to future research findings about Copper(I) bromide,belong copper-catalyst compound

Reference£º
Patent; Pfizer INc.; US5919795; (1999); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1317-39-1,Copper(I) oxide,as a common compound, the synthetic route is as follows.

3-Chloro-4-nitro-benzonitrile Sodium nitrite (6.78 g in water (40 mL) at 0 C.) was slowly added to a solution of 4-amino-3-chloro-benzonitrile (10.5 g) in water (30 mL) and concentrated hydrochloric acid (30 mL) also at 0 C. After 10 minutes the solution was poured onto a suspension of cuprous oxide (3.48 g) and sodium nitrite (31.69 g) in water (100 mL) at 0 C. The ensuing mixture was stirred at 0 C. for 1 hour then at 23 C. for 1 hour. The resulting mixture was extracted with dichloromethane and the organic layer washed with saturated sodium chloride. The separated organic layer was dried over sodium sulfate and then concentrated to give 3-chloro-4-nitro-benzonitrile (11.31 g).

1317-39-1, 1317-39-1 Copper(I) oxide 10313194, acopper-catalyst compound, is more and more widely used in various fields.

Reference£º
Patent; Pfizer Inc.; US2003/78432; (2003); A1;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Copper(I) bromide, A common heterocyclic compound, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route. 7787-70-4

General procedure: The complexes were prepared according to the following method [14]: 1mmol of copper(I) bromide or copper(I) chloride is stirred in methanol until complete dissolution. Then, 2.1mmol of the corresponding phosphine ligand was added. The mixture was stirred at 60C for 30min. under nitrogen atmosphere. A microcrystalline precipitate was obtained by concentration of the solution at reduced pressure. The solid product was dissolved in a dichloromethane/methanol mixture and the solution was gradually cooled to 4C to give an air stable and colorless crystalline solid suitable for X-ray single-crystal diffraction studies.

7787-70-4 Copper(I) bromide 24593, acopper-catalyst compound, is more and more widely used in various fields.

Reference£º
Article; Espinoza, Sully; Arce, Pablo; San-Martin, Enrique; Lemus, Luis; Costamagna, Juan; Farias, Liliana; Rossi, Miriam; Caruso, Francesco; Guerrero, Juan; Polyhedron; vol. 85; (2014); p. 405 – 411;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

7787-70-4, A common heterocyclic compound, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route., 7787-70-4

A dichloromethane (2mL) solution of macrocycle 1 (12mg, 0.05mmol) was allowed to diffuse slowly through a solution of copper bromide (7.2mg, 0.05mmol) in acetonitrile (2mL) at-60C. Slow evaporation of the orange solution at room temperature afforded compound 5, in a quantitative yield, as colorless crystals suitable for an X-ray diffraction analysis. 1H NMR (CDCl3, 300MHz): delta 5.30-5.20 (m, 2H, =CH2), 4.60-2.20 (m, 16H, CH2). BrC10CuH18O2S2 (377.83): calcd C 31.79, H, 4.80; found: C 31.49, H, 4.52.

With the complex challenges of chemical substances, we look forward to future research findings about Copper(I) bromide

Reference£º
Article; Carel, Guillaume; Madec, David; Saponar, Alina; Saffon, Nathalie; Nemes, Gabriela; Rima, Ghassoub; Castel, Annie; Journal of Organometallic Chemistry; vol. 755; (2014); p. 72 – 77;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

The copper-catalyst compound, cas is 142-71-2 name is Copper(II) acetate, mainly used in chemical industry, its synthesis route is as follows.

0.118 g (0.65 mmol) of Cu(OAc)2 was added to a solution of 0.04 g (0.065 mmol)of 2 in 50 mL of DMF. The reaction mixture was refluxed during 2 min and cooled to ambient; five-fold excess of water and NaCl was added. The precipitate was filtered off, washed with water, and dried. Yield 0.04 g (0.059 mmol) of CuTPP., 142-71-2

As the rapid development of chemical substances, we look forward to future research findings about 142-71-2

Reference£º
Article; Maltseva; Zvezdina; Chizhova; Mamardashvili, N. Zh.; Russian Journal of General Chemistry; vol. 86; 1; (2016); p. 102 – 109; Zh. Obshch. Khim.; vol. 86; 1; (2016); p. 110 – 117,8;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”