Tag: M.W:300-400

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.34946-82-2,Copper(II) trifluoromethanesulfonate,as a common compound, the synthetic route is as follows.

2-Phenylpyridine 1a (71 muL, 0.5 mmol),1,2-diphenylethylene 2a (89.7 mg, 0.5 mmol),{[Cp * RhCl2] 2} (3.1 mg, 1 mol%),AgOTf (5.1 mg, 0.02 mmol),Cu (OTf) 2 (180.8 mg, 0.5 mmol)Was added to 2.0 mL of methanol, under argon (1 atm)120 oC reaction after 22 hours to stop the reaction,Diatomaceous earth filter, dichloromethane washing, collecting organic phase evaporated solvent,Methanol / ether / petroleum ether (1: 4: 100) to give the pure isoquinoline salt derivative 3aa. The product was a white solid in 91%, 34946-82-2

The synthetic route of 34946-82-2 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences; Huang, Hanmin; Zhang, Guoyang; (21 pag.)CN104177357; (2017); B;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

As a common heterocyclic compound, it belongs to quinuclidine compound,Quinuclidine-4-carboxylic acid hydrochloride,40117-63-3,Molecular formula: C8H14ClNO290,mainly used in chemical industry, its synthesis route is as follows.,34946-82-2

To a yellow-brown solution of L1 (60 mg, 0.09 mmol) in THF (3 mL)was added a blue solution of [Cu(OTf)2] (36 mg, 0.09 mmol) at roomtemperature. Upon addition the solution colored to dark green. Themixture solution was stirred for 8 h and after filtered, 20 mL of diethylether were then added to the filtrate to precipitate a green solid. Thesolvents were removed by filtration and the residue was washed withether (3¡Á5 mL) and dried in vacuum to yield product 3 as a blue-greenpowder. The formulation of 3 was deduced from elemental analysis asbeing [Cu(H2O)2(L1)](OTf)2, H2O. Yield: 50 mg, 56%. Crystals suitablefor a X-ray diffraction study were obtained by slow vapor diffusion ofEt2O into a CH3CN solution of 3 in a sealed tube. IR (solid, cm-1):nu(NH) 3334 (w), nu(CO) 1654 (w), nu(CF) 1027 (s). UV-Vis (MeCN) lambdamax,nm (epsilon, M-1cm-1): 257 (28110), 284 (26400), 666 (51), EPR (9.30 GHz;CH3CN; 150 K): g//=2.27, g?=2.05, A//=166 G. Elemental analysis calcd (%) for C39H29CuF6N7O8S2. 1 H2O: C, 45.93; H, 3.46; N, 9.62.Found: C, 45.72; H, 3.17; N, 9.23.

With the synthetic route has been constantly updated, we look forward to future research findings about Copper(II) trifluoromethanesulfonate,belong copper-catalyst compound

Reference£º
Article; Ayad, Massinissa; Schollhammer, Philippe; Le Mest, Yves; Wojcik, Laurianne; Petillon, Francois Y.; Le Poul, Nicolas; Mandon, Dominique; Inorganica Chimica Acta; vol. 497; (2019);,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

34946-82-2, Copper(II) trifluoromethanesulfonate is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A methanolic solution of ligand trans-cyclohexane-1,2-diamine(0.1142 g, 1 mmol) was added dropwise to a clear solution ofCopper(II) trifluoromethanesulfonate (0.1808 g, 0.5 mmol) inmethanol (10 mL). The resultant solution was stirred at roomtemperature for 6 h to produce a dark blue coloured solution. Thediffraction quality crystals of the titled complex were obtaineddirectly by slow evaporation of the deep bluish methanolic solutionat room temperature. Yield: 0.272 g, 75%, m.p: 258 C, Anal. Calc. forC14H32CuF6N4O8S2: C, 26.86; H, 5.15; N, 8.95. Found: C, 26.54; H,5.32, N, 8.78. Selected FT-IR (KBr), cm1: n(NH2) 3332e3279, n(CH2)2967e2861, n(OH) 3463, n(CueN) 628, n(CueO) 514. UVeVis [lmax(nm), epsilon (L mol1 cm1)]: 243 (8940), 548 (89)., 34946-82-2

As the paragraph descriping shows that 34946-82-2 is playing an increasingly important role.

Reference£º
Article; Agrahari, Bhumika; Layek, Samaresh; Kumari, Shweta; Anuradha; Ganguly, Rakesh; Pathak, Devendra D.; Journal of Molecular Structure; vol. 1134; (2017); p. 85 – 90;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.34946-82-2,Copper(II) trifluoromethanesulfonate,as a common compound, the synthetic route is as follows.

Ligand L2/L2? (15.2 mg, 63 mumol) was dissolved in ethylacetate (5 mL) and a solution of Cu(OTf)2 (11.4 mg, 31.5mumol) in ethyl acetate (3 mL) was added. The blue precipitatewas isolated by filtration with suction and dried at air;yield: 26 mg (98%). Crystals suitable for X-ray diffractionanalysis were obtained when a solution of the precipitatein the necessary amount of ethyl acetate was concentratedby slow evaporation. M.p. 255.5-256.5C. – IR (KBr): IR(KBr): = 3259 s br (NH), 3151 w, 1643 m, 1591 s, 1500 m,1285 vs, 1243 vs, ~1228 sh, 1159 s, 1028 vs, 720 m, 636 s,574 w, 518 m cm-1. – MS ((+)-MALDI-TOF): m/z (%) = 694.15(100) [M-CF3SO3]+, 1539.24 (8) [2 [CuL2L2?(OTf)2]-OTf]. -Anal. for C28H30CuF6N10O6S2 (844.27), water-free sample:calcd. C 39.83, H 3.58, N 16.59; S 7.59; found C 39.62, H 3.41,N 16.64, S 7.61., 34946-82-2

The synthetic route of 34946-82-2 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Schroeder, Sven; Frey, Wolfgang; Maas, Gerhard; Zeitschrift fur Naturforschung, B: Chemical Sciences; vol. 71; 6; (2016); p. 683 – 696;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.34946-82-2,Copper(II) trifluoromethanesulfonate,as a common compound, the synthetic route is as follows.

The molar ratio of Cu (CF3SO3) 2 and 4- (3- (4H-1,2,4-triazol-4-yl) phenyl) -4H-1,2,4-triazole) (L)For 1: 1;L (0.0424 g, 0.2 mmol), Cu (CF3SO3) 2 (0.0691 g, 0.2 mmol), H2O (6 mL)CH3CN (4 mL), water heat 100 oC three days later slowly to room temperature.After the opening, there are yellow rod-like crystals suitable for X-ray single crystal diffraction analysis. Yield: 35% (based on L calculation).

34946-82-2, The synthetic route of 34946-82-2 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Tianjin Normal University; Wang, Ying; (11 pag.)CN104557984; (2017); B;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Copper(II) trifluoromethanesulfonate, cas is 34946-82-2, it is a common heterocyclic compound, the copper-catalyst compound, its synthesis route is as follows.,34946-82-2

To a solution of 6.90 g (18.5 mmol) of 5′-bromo-3′-nitro-3,4,5,6-tetrahydro-2H- [l,2′]bipyridinyl-4-yl)-acetic acid in dimethylsulfoxide (100 mL) is added 4.5 mL (41 mmol) of dimethylethylenediamine followed by 4.0 g (39 mmol) of sodiummethanesulfinate and 5.5 g (19 mmol) of copper (II) triflate. The mixture is heated to 130 C for lhour then cooled to room temperature. The mixture is diluted with water and stirred overnight during which time a solid precipitates from solution. The yellow solid is collected by filtration, washed with water and dried on the filter pad to provide 5.00 g (72.6%) of (5′-methanesulfonyl-3′-nitro-3,4,5,6-tetrahydro-2H-[l,2′]bipyridinyl-4-yl)- acetic acid ethyl ester.

34946-82-2 is used more and more widely, we look forward to future research findings about Copper(II) trifluoromethanesulfonate

Reference£º
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; GINN, John David; SORCEK, Ronald John; TURNER, Michael Robert; WU, Di; WU, Frank; WO2011/84985; (2011); A1;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

34946-82-2, Copper(II) trifluoromethanesulfonate is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a solution of 6.90 g (18.5 mmol) of 5′-bromo-3′-nitro-3,4,5,6-tetrahydro-2H- [l,2′]bipyridinyl-4-yl)-acetic acid in dimethylsulfoxide (100 mL) is added 4.5 mL (41 mmol) of dimethylethylenediamine followed by 4.0 g (39 mmol) of sodiummethanesulfinate and 5.5 g (19 mmol) of copper (II) triflate. The mixture is heated to 130 C for lhour then cooled to room temperature. The mixture is diluted with water and stirred overnight during which time a solid precipitates from solution. The yellow solid is collected by filtration, washed with water and dried on the filter pad to provide 5.00 g (72.6%) of (5′-methanesulfonyl-3′-nitro-3,4,5,6-tetrahydro-2H-[l,2′]bipyridinyl-4-yl)- acetic acid ethyl ester.

34946-82-2, 34946-82-2 Copper(II) trifluoromethanesulfonate 2734996, acopper-catalyst compound, is more and more widely used in various fields.

Reference£º
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; GINN, John David; SORCEK, Ronald John; TURNER, Michael Robert; WU, Di; WU, Frank; WO2011/84985; (2011); A1;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

34946-82-2, Copper(II) trifluoromethanesulfonate is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

The ligand (75.9 mg, 0.12 mmol) was dissolved in THF (4 ml) and added to a suspension of sodium hydride (11.8 mg, 0.49 mmol) in THF (2 ml) at 0 C. The resulting yellow mixture was stirred at 0 C for 1 h and at r. t. for 2 h. Afterwards the solution was added dropwise to a solution of copper(II) triflate (44.3 mg, 0.12 mmol) in THF (2 ml). The dark brown solution was stirred at r. t. for 16 h. After filtration the solvent was removed in vacuo and the brown solid purified by recrystallisation from dichloromethane and pentane. 6: 60.8 mg, 60.9%. C41H36N5O5SF3Cu¡¤3CH2Cl2: Anal. Calc. C, 46.35; H, 4.24; N, 6.14. Found: C, 46.70; H, 4.12; N, 6.19%. HR-MS: C40H36N5O2Cu Calc. 681.2159. Found: 681.2148 (100.0), IR: nunu [cm-1]=3060, 2929, 2855, 1640, 1592, 1530, 1444, 1262, 1174, 1097, 1044, 879, 646., 34946-82-2

The synthetic route of 34946-82-2 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Sauer, Desiree C.; Wadepohl, Hubert; Polyhedron; vol. 81; (2014); p. 180 – 187;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.34946-82-2,Copper(II) trifluoromethanesulfonate,as a common compound, the synthetic route is as follows.

L (0.0424 g, 0.2 mmol), Cu (CF3SO3)2(0.0691g,0.2mmol)H2O (6 mL), CH3CN (4 mL), water and heat 100Oslow C down to room temperature after three days.After opening the autoclave there for X- ray diffraction analysis of the yellow rod-like crystals.Yield: 35%

34946-82-2, 34946-82-2 Copper(II) trifluoromethanesulfonate 2734996, acopper-catalyst compound, is more and more widely used in various fields.

Reference£º
Patent; Tianjin Normal University; Wang, Ying; (10 pag.)CN104557986; (2016); B;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.34946-82-2,Copper(II) trifluoromethanesulfonate,as a common compound, the synthetic route is as follows.

A mixture of Cu(CF3SO3)2 (200 mg, 0.55 mmol) and ligand L(190 mg, 0.55 mmol) in a mixture of MeOH:CH2Cl2 in 1:1 volumeratio (30 mL) was stirred at room temperature for 24 h. The productwas isolated by evaporation of solvents and recrystallization of the residuefrom a minimum volume of MeOH by the gradual addition ofdiethyl ether to obtain complex 5 as a green solid. Crystal appropriatefor X-ray diffraction was obtained by vial to vial diffusion at 4 C.Yield: 80.3% (335 mg, 0.44 mmol).ESI-MS: m/z (%) = 345 [H + L]+ (100), 407 [Cu(L-H)]+ (90). IR(KBr): nu(CH)ar 3053; nuas(CH3) 2972; nus(CH3) 2877; nu(C=N)imin1553; nu(C=C)ar 1581, 1547, 1525, nu(CN) 1488, 1422; nu(C=N)ar1279, 1235, rho(CH)ar 1187, 1172, 1137; gamma(CH)ar 891, 782, 723,551 cm-1. Anal. calc. for [Cu(C20H16N4S)(CF3SO3)(MeOH)(H2O)](CF3SO3)] (756.17): C, 36.53; H, 2.93; N, 7.41; Found: C, 36.40; H, 2.99;N, 7.35%.

34946-82-2, 34946-82-2 Copper(II) trifluoromethanesulfonate 2734996, acopper-catalyst compound, is more and more widely used in various fields.

Reference£º
Article; Bocian, Aleksandra; Gorczy?ski, Adam; Marcinkowski, Damian; Witomska, Samanta; Kubicki, Maciej; Mech, Paulina; Bogunia, Ma?gorzata; Brzeski, Jakub; Makowski, Mariusz; Pawlu?, Piotr; Patroniak, Violetta; Journal of Molecular Liquids; vol. 302; (2020);,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”